Simple Summary Integrins, a superfamily of cell adhesion receptors, were extensively
investigated as therapeutic targets over the last decades, motivated by their multiple …

Tumor progression involves invasion, migration, metabolism, autophagy, exosome
secretion, and drug resistance. Cargos transported by membrane vesicle trafficking underlie …

Neutrophils are the most prevalent leukocytes in the human body. They have a pivotal role
in the innate immune response against invading bacterial and fungal pathogens, while …

Spatially controlled, cargo-specific endocytosis is essential for development, tissue
homeostasis and cancer invasion. Unlike cargo-specific clathrin-mediated endocytosis, the …

Integrin-mediated adhesion of cells to the extracellular matrix (ECM) is crucial for the
physiological development and functioning of tissues but is pathologically disrupted in …

Localization of RNAs at protrusive regions of cells is important for single-cell migration on
two-dimensional surfaces. Protrusion-enriched RNAs encode factors linked to cancer …

Membrane proteins constitute the filter that controls the cellular traffic of nutrients, ions and
other essential molecules, as well as the transmission of signals across the membrane …

Numerous RNA s exhibit specific distribution patterns in mammalian cells. However, the
functional and mechanistic consequences are relatively unknown. Here, we investigate the …

Integrins are transmembrane proteins that are most typically thought of as integrating
adhesion to the extracellular matrix with intracellular signaling and cell regulation …

Extracellular vesicles (EVs) are important mediators of embryo attachment and outgrowth
critical for successful implantation. While EVs have garnered immense interest in their …