Ferroptosis is a distinct lipid peroxidation-dependent form of necrotic cell death. This
process has been increasingly contemplated as a new target for cancer therapy because of …

Ferroptosis, an iron-dependent form of regulated cell death, is emerging as a crucial
regulator of human physiology and pathology. Increasing evidence showcases a reciprocal …

Pancreatic ductal adenocarcinoma (PDA) cells reprogram both mitochondrial and lysosomal
functions to support growth. At the same time, this causes significant dishomeostasis of free …

Ferroptosis is an iron-dependent form of cell death that results from excess lipid peroxidation
in cellular membranes. Within the last decade, physiological and pathological roles for …

Coenzyme Q10 (CoQ10) plays a key role in many aspects of cellular metabolism. For
CoQ10 to function normally, continual interconversion between its oxidised (ubiquinone) …

Ferroptosis, a unique form of regulated cell death driven by iron-dependent lethal lipid
peroxidation, is implicated in various stress-related diseases like neurodegeneration …

Selenium (Se) is an essential trace element for humans and animals, but high-dose
supplementation with Se compounds, most notably selenite, may exert cytotoxic and other …

Cell death is a normal physiological process within cells that involves multiple pathways,
such as normal DNA damage, cell cycle arrest, and programmed cell death (PCD). Cell …

Ovarian cancer (OV) ranks among the deadliest gynecological cancer, known for its high risk
of relapse and metastasis, and a general resistance to conventional platinum‐based …

During metastasis, cancer cells detach from the primary tumor, circulate through the
bloodstream, and establish themselves at distant sites, facing increased levels of reactive …