Vitamin D has been described as an essential nutrient and hormone, which can cause
nuclear, non-genomic, and mitochondrial effects. Vitamin D not only controls the …

Background: Acute kidney injury (AKI) constitutes a multi-factorially caused condition, which
significantly affects kidney function and can lead to elevated risk of morbidity and mortality …

We previously reported the effect of dioscin against hepatic ischemia/reperfusion injury (IRI)
in rats. However, little is known concerning the role of dioscin in renal IRI. In the present …

We investigated the involvement of peroxisome proliferator activated receptor-γ (PPAR-
γ)/endothelial nitric oxide synthase (eNOS) pathway in estradiol mediated protection against …

Renal ischemia-reperfusion injury (I/RI) remains a critical clinical situation. Several evidence
revealed the potential reno-protective effects of Vitamin D and/or pioglitazone, on renal I/RI …

Acute kidney injury (AKI) is a common complication in patients with potentially life-
threatening diseases, and it is also usually associated with unacceptable morbidity and …

Demethylase Tet2 plays a vital role in the immune response. Acute kidney injury (AKI)
initiation and maintenance phases are marked by inflammatory responses and leukocyte …

The main objective of this study was to determine if the telmisartan-ameliorative effects of
metabolic syndrome (MetS)-evoked nephropathy are attributed to the Hippo pathway. A …

The present study was designed to investigate the role of glycine in ischemia reperfusion-
induced acute kidney injury (AKI) in rats. The AKI was induced in rats by occluding renal …

Background Sildenafil is a phosphodiesterase inhibitor used clinically for treating erectile
dysfunction. Few studies suggest sildenafil to be a renoprotective agent. The present study …