Modeling identifies variability in SARS-CoV-2 uptake and eclipse phase by infected cells as principal drivers of extreme variability in nasal viral load in the 48 h post …
The SARS-CoV-2 coronavirus continues to evolve with scores of mutations of the spike,
membrane, envelope, and nucleocapsid structural proteins that impact pathogenesis …
membrane, envelope, and nucleocapsid structural proteins that impact pathogenesis …
The power of weak, transient interactions across biology: A paradigm of emergent behavior
A growing list of diverse biological systems and their equally diverse functionalities provides
realizations of a paradigm of emergent behavior. In each of these biological systems …
realizations of a paradigm of emergent behavior. In each of these biological systems …
A hybrid discrete-continuum model of immune responses to SARS-CoV-2 infection in the lung alveolar region, with a focus on interferon induced innate response
We develop a lattice-based, hybrid discrete-continuum modeling framework for SARS-CoV-
2 exposure and infection in the human lung alveolar region, or parenchyma, the massive …
2 exposure and infection in the human lung alveolar region, or parenchyma, the massive …
A SARS-CoV-2 nanoparticle vaccine based on chemical conjugation of loxoribine and SpyCatcher/SpyTag
W Yan, W Yu, L Shen, L Xiao, J Qi, T Hu - International Journal of Biological …, 2023 - Elsevier
SARS-CoV-2 is a particularly transmissible virus that renders the worldwide COVID-19
pandemic and global severe respiratory distress syndrome. Protein-based vaccines hold …
pandemic and global severe respiratory distress syndrome. Protein-based vaccines hold …
[HTML][HTML] Protein biomarker detection via differential dynamic microscopy
We demonstrate a pioneering application of differential dynamic microscopy (DDM) for
disease diagnosis by monitoring the dynamic signal of probe beads. When the target …
disease diagnosis by monitoring the dynamic signal of probe beads. When the target …
[PDF][PDF] Novel polymer-based hydrogels of recent research in drug delivery for disease treatment related to SARS-CoV-2 virus.
NH Thang, N Van Phuc, TTT Nhi… - Express Polymer …, 2024 - researchgate.net
Polymer-based hydrogels are hydrophilic polymer networks with a remarkable capacity to
absorb substantial amounts of water and biological fluids, rendering them highly attractive …
absorb substantial amounts of water and biological fluids, rendering them highly attractive …
Allometric Comparison of Viral Dynamics in the Nasal Cavity-Nasopharyngeal Mucus Layer of Human and Rhesus Monkey by CFD-HCD Approach
Abstract Background and Objective Viral respiratory infections stand as a considerable
global health concern, presenting significant risks to the health of both humans and animals …
global health concern, presenting significant risks to the health of both humans and animals …
[HTML][HTML] Computational Modeling Insights into Extreme Heterogeneity in COVID-19 Nasal Swab Data
L Zhang, H Cao, K Medlin, J Pearson, AC Aristotelous… - Viruses, 2023 - mdpi.com
Throughout the COVID-19 pandemic, an unprecedented level of clinical nasal swab data
from around the globe has been collected and shared. Positive tests have consistently …
from around the globe has been collected and shared. Positive tests have consistently …
[PDF][PDF] New Challenges in the Mathematical Modelling and Control of COVID-19 Epidemics: Analysis of Non-Pharmaceutical Actions and Vaccination Strategies
CM Verrelli, F Della Rossa - Mathematics, 2024 - mdpi.com
Since its official appearance in China in December 2019, COVID-19 (SARS-CoV-2)
immediately reached pandemic proportions on six continents and in over 195 countries. It …
immediately reached pandemic proportions on six continents and in over 195 countries. It …