Molecular Pathogenesis of Klebsiella Pneumoniae

B Li, Y Zhao, C Liu, Z Chen, D Zhou - Future microbiology, 2014 - Taylor & Francis
Typical Klebsiella pneumoniae is an opportunistic pathogen, which mostly affects those with
weakened immune systems and tends to cause nosocomial infections. A subset of …

Prophylaxis and Treatment against Klebsiella pneumoniae: Current Insights on This Emerging Anti-Microbial Resistant Global Threat

V Arato, MM Raso, G Gasperini… - International Journal of …, 2021 - mdpi.com
Klebsiella pneumoniae (Kp) is an opportunistic pathogen and the leading cause of
healthcare-associated infections, mostly affecting subjects with compromised immune …

Identification of a second glycoform of the clinically prevalent O1 antigen from Klebsiella pneumoniae

SD Kelly, OG Ovchinnikova, F Müller… - Proceedings of the …, 2023 - National Acad Sciences
Carbapenemase and extended β-lactamase-producing Klebsiella pneumoniae isolates
represent a major health threat, stimulating increasing interest in immunotherapeutic …

The diversity of Klebsiella pneumoniae surface polysaccharides

R Follador, E Heinz, KL Wyres… - Microbial …, 2016 - microbiologyresearch.org
Klebsiella pneumoniae is considered an urgent health concern due to the emergence of
multi-drug-resistant strains for which vaccination offers a potential remedy. Vaccines based …

The revitalization of antimicrobial peptides in the resistance era

Y Liu, J Shi, Z Tong, Y Jia, B Yang, Z Wang - Pharmacological Research, 2021 - Elsevier
The antibiotic resistance crisis is becoming incredibly thorny due to the indiscriminate
employment of antibiotics in agriculture and aquaculture, such as growth promoters, and the …

Role of Bacterial Surface Structures on the Interaction of Klebsiella pneumoniae with Phagocytes

C March, V Cano, D Moranta, E Llobet… - PloS one, 2013 - journals.plos.org
Phagocytosis is a key process of the immune system. The human pathogen Klebsiella
pneumoniae is a well known example of a pathogen highly resistant to phagocytosis. A …

Targeting the Sugary Armor of Klebsiella Species

LPP Patro, T Rathinavelan - Frontiers in cellular and infection …, 2019 - frontiersin.org
The emergence of multidrug-resistant strains of Gram-negative Klebsiella species is an
urgent global threat. The World Health Organization has listed Klebsiella pneumoniae as …

The structures of core regions from enterobacterial lipopolysaccharides–an update

O Holst - FEMS microbiology letters, 2007 - academic.oup.com
To the major virulence factors of Gram-negative bacteria belong the lipopolysaccharides
(endotoxins), which are very well characterized for their immunological, pharmacological …

LPS O antigen plays a key role in Klebsiella pneumoniae capsule retention

S Singh, JJ Wilksch, RA Dunstan, A Mularski… - Microbiology …, 2022 - Am Soc Microbiol
Despite the importance of encapsulation in bacterial pathogenesis, the biochemical
mechanisms and forces that underpin retention of capsule by encapsulated bacteria are …

Secondary acylation of Klebsiella pneumoniae lipopolysaccharide contributes to sensitivity to antibacterial peptides

A Clements, D Tull, AW Jenney, JL Farn, SH Kim… - Journal of Biological …, 2007 - ASBMB
Klebsiella pneumoniae is an important cause of nosocomial Gram-negative sepsis.
Lipopolysaccharide (LPS) is considered to be a major virulence determinant of this …