Light sources and dosimetry techniques for photodynamic therapy

MM Kim, A Darafsheh - Photochemistry and photobiology, 2020 - Wiley Online Library
Effective treatment delivery in photodynamic therapy (PDT) requires coordination of the light
source, the photosensitizer, and the delivery device appropriate to the target tissue. Lasers …

The role of photodynamic therapy (PDT) physics

TC Zhu, JC Finlay - Medical physics, 2008 - Wiley Online Library
Photodynamic therapy (PDT) is an emerging treatment modality that employs the
photochemical interaction of three components: light, photosensitizer, and oxygen …

Explicit dosimetry for photodynamic therapy: macroscopic singlet oxygen modeling

KKH Wang, JC Finlay, TM Busch… - Journal of …, 2010 - Wiley Online Library
Abstract Singlet oxygen (1O2) is the major cytotoxic agent responsible for cell killing for type‐
II photodynamic therapy (PDT). An empirical four‐parameter macroscopic model is …

On the in vivo photochemical rate parameters for PDT reactive oxygen species modeling

MM Kim, AA Ghogare, A Greer… - Physics in Medicine & …, 2017 - iopscience.iop.org
Photosensitizer photochemical parameters are crucial data in accurate dosimetry for
photodynamic therapy (PDT) based on photochemical modeling. Progress has been made …

A Critical Review for Synergic Kinetics and Strategies for Enhanced Photopolymerizations for 3D-Printing and Additive Manufacturing

JT Lin, J Lalevee, DC Cheng - Polymers, 2021 - mdpi.com
The synergic features and enhancing strategies for various photopolymerization systems are
reviewed by kinetic schemes and the associated measurements. The important topics …

In-vivo singlet oxygen threshold doses for PDT

TC Zhu, MM Kim, X Liang, JC Finlay… - Photonics & lasers in …, 2015 - degruyter.com
Objective: Dosimetry of singlet oxygen (1O2) is of particular interest because it is the major
cytotoxic agent causing biological effects of type-II photosensitizers during photodynamic …

Study of tissue oxygen supply rate in a macroscopic photodynamic therapy singlet oxygen model

TC Zhu, B Liu, R Penjweini - Journal of biomedical optics, 2015 - spiedigitallibrary.org
An appropriate expression for the oxygen supply rate (Γ s) is required for the macroscopic
modeling of the complex mechanisms of photodynamic therapy (PDT). It is unrealistic to …

Macroscopic singlet oxygen modeling for dosimetry of Photofrin-mediated photodynamic therapy: an in-vivo study

H Qiu, MM Kim, R Penjweini… - Journal of biomedical …, 2016 - spiedigitallibrary.org
Although photodynamic therapy (PDT) is an established modality for cancer treatment,
current dosimetric quantities, such as light fluence and PDT dose, do not account for the …

Efficacy S-formula and Kinetics of Non-oxygen-mediated (Type-I) and Oxygen-mediated (Type-II) Corneal Cross-linking

JT Lin - Ophthalmology Research: An International Journal, 2018 - publish.sub7journal.com
Aims: To derive analytic formulas for the overall efficacy of corneal collagen crosslinking
(CXL) based on coupled kinetic equations including both non-oxygen-mediated (NOM) and …

Pulse mode of laser photodynamic treatment induced cell apoptosis

VV Klimenko, NA Knyazev, FV Moiseenko… - Photodiagnosis and …, 2016 - Elsevier
One of the factors limiting photodynamic therapy (PDT) is hypoxia in tumor cells during
photodynamic action. PDT with pulse mode irradiation and appropriate irradiation …