Diabetes insipidus (DI) is a disorder characterized by excretion of large amounts of
hypotonic urine. Central DI results from a deficiency of the hormone arginine vasopressin …

Hyponatremia is defined as a decrease in the serum sodium concentration to a level below
136 mmol per liter. Whereas hypernatremia always denotes hypertonicity, hyponatremia can …

This article provides a comprehensive review of dehydration assessment and presents a
unique evaluation of the dehydration and performance literature. The importance of …

Lang, Florian, Gillian L. Busch, Markus Ritter, Harald Völkl, Siegfried Waldegger, Erich
Gulbins, and Dieter Häussinger. Functional Significance of Cell Volume Regulatory …

Cerebral edema contributes significantly to morbidity and death associated with many
common neurological disorders. However, current treatment options are limited to …

The brain is unique among organs in many respects, including its mechanisms of lipid
synthesis and energy production. The nervous system-specific metabolite N-acetylaspartate …

The serum sodium concentration and thus serum osmolality are closely controlled by water
homeostasis, which is mediated by thirst, arginine vasopressin, and the kidneys. 1 A …

Disorders of body fluids are among the most commonly encountered problems in the
practice of clinical medicine. This is in large part because many different disease states can …

Inositol phospholipids and inositol phosphates mediate well‐established functions in signal
transduction and in Ca2+ homeostasis in the CNS and non‐neural tissues. More recently …

Metabolic syndrome and diabetes impact brain function and metabolism. While it is well
established that rodents exposed to diets rich in saturated fat develop brain dysfunction …