Interoception refers to the representation of the internal states of an organism, and includes
the processes by which it senses, interprets, integrates, and regulates signals from within …

Modern optogenetics can be tuned to evoke activity that corresponds to naturally occurring
local or global activity in timing, magnitude or individual-cell patterning. This outcome has …

Vagal sensory neurons constitute the major afferent supply to the airways and lungs.
Subsets of afferents are defined by their embryological origin, molecular profile …

The mammalian nervous system is comprised of a seemingly infinitely complex network of
specialized synaptic connections that coordinate the flow of information through it. The field …

Bronchopulmonary C-fibers and a subset of mechanically sensitive, acid-sensitive
myelinated sensory nerves play essential roles in regulating cough. These vagal sensory …

Chronic cough is a common symptom that can be a daunting challenge for clinicians since
treatment of the underlying cause does not always provide adequate relief, an obvious …

Opioid-induced respiratory depression (OIRD) represents the primary cause of death
associated with therapeutic and recreational opioid use. Within the United States, the rate of …

Known as the gas exchange organ, the lung is also critical for responding to the aerosol
environment in part through interaction with the nervous system. The diversity and specificity …

Cerebellar outputs take polysynaptic routes to reach the rest of the brain, impeding
conventional tracing. Here, we quantify pathways between the cerebellum and forebrain by …

Coughing is a respiratory behavior that plays a crucial role in protecting the respiratory
system. Here we show that the nucleus of the solitary tract (NTS) in mice contains …