The development of the mammalian cerebellum is orchestrated by both cell-autonomous
programs and inductive environmental influences. Here, we describe the main processes of …

Granule cells (GCs) are the most numerous cell type in the cerebellum and indeed, in the
brain: at least 99% of all cerebellar neurons are granule cells. In this review article, we first …

We have utilized an in vivo-inducible genetic-fate-mapping strategy to permanently label
cohorts of Math1-positive cells and their progeny that arise in the rhombic lip of the …

Recent advances in molecular biology have drastically changed our vision on the
development of the nervous system, the cerebellum in particular. After a classical descriptive …

The cerebellum is one of the best studied parts of the brain. The cerebellar cortex is
composed of four main types of neurons: granule cells, Purkinje cells, and two types of …

In most tissues, the precise control of cell migration and cell-cell interaction is of paramount
importance to the development of a functional structure. Several families of secreted …

The cerebellum is a key player in many brain functions and a major topic of neuroscience
research. However, the cerebellar nuclei (CN), the main output structures of the cerebellum …

The generation and targeting of appropriate numbers and types of neurons to where they
are needed in the brain is essential for the establishment, maintenance and modification of …

During development, precerebellar neurons migrate dorsoventrally from the rhombic lip to
the floor plate. Some of these neurons cross the midline while others stop. We have …

Several independent lines of evidence have revealed an instructive role for retinoic acid
(RA) signalling in the establishment of normal pattern and cellular specification of the …