Targeting vascular (endothelial) dysfunction

A Daiber, S Steven, A Weber… - British journal of …, 2017 - Wiley Online Library
Cardiovascular diseases are major contributors to global deaths and disability‐adjusted life
years, with hypertension a significant risk factor for all causes of death. The endothelium that …

Assessment of resistance vessel function in human skeletal muscle: guidelines for experimental design, Doppler ultrasound, and pharmacology

JK Limberg, DP Casey, JD Trinity… - American Journal …, 2020 - journals.physiology.org
The introduction of duplex Doppler ultrasound almost half a century ago signified a
revolutionary advance in the ability to assess limb blood flow in humans. It is now widely …

CORP: Ultrasound assessment of vascular function with the passive leg movement technique

JR Gifford, RS Richardson - Journal of applied physiology, 2017 - journals.physiology.org
As dysfunction of the vascular system is an early, modifiable step in the progression of many
cardiovascular diseases, there is demand for methods to monitor the health of the vascular …

Understanding the mechanisms of disease modifying effects of aerobic exercise in people with Alzheimer's disease

A Abdullahi, TWL Wong, SSM Ng - Ageing Research Reviews, 2024 - Elsevier
Alzheimer's disease (AD) is a very disabling disease. Pathologically, it is characterized by
the presence of amyloid plaques and neurofibrillary tangles in the brain that results in …

Physiological impact and clinical relevance of passive exercise/movement

JD Trinity, RS Richardson - Sports Medicine, 2019 - Springer
Passive exercise/movement has a long history in both medicine and physiology. Early
clinical applications of passive exercise/movement utilized pneumatic and direct limb …

[HTML][HTML] Acute dietary nitrate supplementation improves flow mediated dilatation of the superficial femoral artery in healthy older males

MA Walker, TG Bailey, L McIlvenna, JD Allen, DJ Green… - Nutrients, 2019 - mdpi.com
Aging is often associated with reduced leg blood flow, increased arterial stiffness, and
endothelial dysfunction, all of which are related to declining nitric oxide (NO) bioavailability …

[HTML][HTML] Exercise training improves vascular function in patients with Alzheimer's disease

A Pedrinolla, M Venturelli, C Fonte, S Tamburin… - European Journal of …, 2020 - Springer
Purpose Vascular dysfunction has been demonstrated in patients with Alzheimer's disease
(AD). Exercise is known to positively affect vascular function. Thus, the aim of our study was …

Influence of dietary inorganic nitrate on blood pressure and vascular function in hypertension: prospective implications for adjunctive treatment

RM Broxterman, DT La Salle, J Zhao… - Journal of Applied …, 2019 - journals.physiology.org
Dietary inorganic nitrate (nitrate) is a promising adjunctive treatment to reduce blood
pressure and improve vascular function in hypertension. However, it remains unknown if the …

Single passive leg movement assessment of vascular function: contribution of nitric oxide

RM Broxterman, JD Trinity, JR Gifford… - Journal of Applied …, 2017 - journals.physiology.org
The assessment of passive leg movement (PLM)-induced leg blood flow (LBF) and vascular
conductance (LVC) is a novel approach to assess vascular function that has recently been …

Heart and musculoskeletal hemodynamic responses to repetitive bouts of quadriceps static stretching

M Venturelli, S Rampichini… - Journal of Applied …, 2019 - journals.physiology.org
The role of sympathetic and parasympathetic activity in relation to the repetitive exposure to
static stretching (SS) on heart and musculoskeletal hemodynamics in stretched and resting …