Parkinson's disease and cardiovascular involvement: Edifying insights

L Grosu, AI Grosu, D Crisan, A Zlibut… - Biomedical …, 2023 - spandidos-publications.com
Parkinson's disease (PD) is one of the most common neurodegenerative illnesses, and is a
major healthcare burden with prodigious consequences on life‑quality, morbidity, and …

[HTML][HTML] PET imaging in animal models of Parkinson's disease

R Ni - Behavioural Brain Research, 2023 - Elsevier
Alpha-synucleinopathies, such as Parkinson's disease, dementia with Lewy bodies and
multiple system atrophy, are characterized by aberrant accumulation of alpha-synuclein and …

Sudden cardiac death in synucleinopathies

K Javanshiri, T Drakenberg, M Haglund… - … of Neuropathology & …, 2023 - academic.oup.com
The purpose of this study was to investigate the cause of death in subjects with α-
synucleinopathies (ASs) and the confirmed presence of cardiac α-synuclein (α-syn) …

Exploring the prevalence of undetected bradyarrhythmia in dementia with Lewy bodies

I Heyman, T Persson, M Haglund, E Londos - Clinical Autonomic …, 2023 - Springer
Purpose To explore the prevalence of undetected bradyarrhythmia in a cohort of people with
dementia with Lewy bodies. Methods Thirty participants diagnosed with dementia with Lewy …

[HTML][HTML] α-Synuclein pathology from the body to the brain: so many seeds so close to the central soil

Y Yang, Z Zhang - Neural Regeneration Research, 2024 - journals.lww.com
Abstract α-Synuclein is a protein that mainly exists in the presynaptic terminals. Abnormal
folding and accumulation of α-synuclein are found in several neurodegenerative diseases …

[HTML][HTML] Alpha Synuclein Toxicity and Non-Motor Parkinson's

GM Mazzotta, C Conte - Cells, 2024 - mdpi.com
Parkinson's disease (PD) is a common multisystem neurodegenerative disorder affecting
1% of the population over the age of 60 years. The main neuropathological features of PD …

大脑外病理性α-突触核蛋白: 这么多种子离源泉这么近

Y Yang, Z Zhang - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
α-突触核蛋白是一种主要存在于突触前末端的蛋白. 在包括帕金森病在内的多种神经退行性疾病
中, 已发现了α-突触核蛋白存在异常折叠和积聚. 聚集和高度磷酸化的α-突触核蛋白是大脑中 …

A stargazer's guide to neurodegeneration: Astrocytes' role in the propagation of pathological proteins

T Mothes - 2024 - diva-portal.org
Abstract Mothes, T. 2024. A stargazer's guide to neurodegeneration. Astrocytes' role in the
propagation of pathological proteins. Digital Comprehensive Summaries of Uppsala …

Clinical and Non-Clinical Cardiovascular Disease Associated Pathologies in Parkinson's Disease

B Lee, C Edling, S Ahmad, FEN LeBeau, G Tse… - International Journal of …, 2023 - mdpi.com
Despite considerable breakthroughs in Parkinson's disease (PD) research, understanding of
non-motor symptoms (NMS) in PD remains limited. The lack of basic level models that can …