Critical limb ischemia (CLI) constitutes the most severe form of peripheral arterial disease
(PAD), it is characterized by progressive blockade of arterial vessels, commonly correlated …

Pathologies of the vasculature including the microvasculature are often complex in nature,
leading to loss of physiological homeostatic regulation of patency and adequate perfusion to …

Diabetic patients with critical limb ischemia face a high rate of limb amputation.
Regeneration of the vasculature and skeletal muscles can salvage diseased limbs. Therapy …

Intracerebral hemorrhage is a highly prevalent and prognostically poor disease, imposing
immeasurable harm on human life and health. However, the treatment options for …

Diabetes is a key risk factor for ischaemic foot disease, which causes pain, tissue loss,
hospital admission, and major amputation. Currently, treatment focuses on …

Cell therapies involving the administration of bone marrow-derived mononuclear cells (BM-
MNCs) for patients with chronic limb-threatening ischemia (CLTI) have shown promise; …

Autologous cell therapy (ACT) is primarily used in diabetic patients with chronic limb-
threatening ischemia (CLTI) who are not candidates for standard revascularization …

Peripheral artery disease (PAD) affects more than 230 million people worldwide, with
approximately 11% of patients presenting with advanced-stage PAD or critical limb ischemia …

Despite the improvements in endovascular techniques during the last decades, there is still
an increase in the prevalence of peripheral artery disease (PAD) with limited practical …

Objective The treatment of chronic limb threatening ischemia (CLTI) involves a broad
spectrum of therapies including many new and emerging techniques. To standardize results …