Receptor tyrosine kinase activation: From the ligand perspective
Receptor tyrosine kinases (RTKs) are single-span transmembrane receptors in which
relatively conserved intracellular kinase domains are coupled to divergent extracellular …
relatively conserved intracellular kinase domains are coupled to divergent extracellular …
Epidermal growth factor receptor: Structure-function informing the design of anticancer therapeutics
RA Mitchell, RB Luwor, AW Burgess - Experimental cell research, 2018 - Elsevier
Research on the epidermal growth factor (EGF) family and the family of receptors (EGFR)
has progressed rapidly in recent times. New crystal structures of the ectodomains with …
has progressed rapidly in recent times. New crystal structures of the ectodomains with …
Basic Amino Acids Within the Juxtamembrane Domain of the Epidermal Growth Factor Receptor Regulate Receptor Dimerization and Auto-phosphorylation
JD Mohr, A Wagenknecht-Wiesner, DA Holowka… - The protein journal, 2020 - Springer
Epidermal growth factor receptor (EGFR) dysregulation is observed in many human cancers
and is both a cause of oncogenesis and a target for chemotherapy. We previously showed …
and is both a cause of oncogenesis and a target for chemotherapy. We previously showed …
[PDF][PDF] Research Publication Repository
RA Mitchell, RB Luwor, AW Burgess - 2018 - publications.wehi.edu.au
Research on the epidermal growth factor (EGF) family and the family of receptors (EGFR)
has progressed rapidly in recent times. New crystal structures of the ectodomains with …
has progressed rapidly in recent times. New crystal structures of the ectodomains with …