As the most dominant cell type in the skin, keratinocytes play critical roles in wound repair
not only as structural cells but also exerting important immune functions. This review focuses …

Abstract Machine learning (ML) is a rapidly advancing field with increasing utility in health
care. We conducted a systematic review and critical appraisal of ML applications in vascular …

Background: Software systems using artificial intelligence for medical purposes have been
developed in recent years. The success of deep neural networks (DNN) in 2012 in the …

Objectives The incidence of type 2 diabetes mellitus has increased significantly in recent
years. With the development of artificial intelligence applications in healthcare, they are …

Diabetic foot ulcers (DFUs) are a serious complication for people with diabetes. They result
in increased morbidity and pressures on health system resources. Developments in …

In the past decade diabetes management has been transformed by the addition of
continuous glucose monitoring and insulin pump data. More recently, a wide variety of …

Single-nucleotide polymorphisms (SNPs) in the Toll-like receptor 4 (TLR4) gene have been
documented in type 2 diabetes mellitus (T2DM) and other diseases in the Saudi population …

Bacterial toxins are thought to play a role in delayed wound healing in critically colonised
and infected wounds. Endotoxins are released from Gram-negative bacteria when they are …

Diabetic foot syndrome is a multifactorial pathology with at least three main etiological
factors, ie, peripheral neuropathy, peripheral arterial disease, and infection. In addition to …

We tried to unveil the clinical significance of miR-146a as a biomarker in M2 macrophage
polarization in diabetic wound healing. Initially, we found reduced miR-146a in …