Glomerular hyperfiltration: definitions, mechanisms and clinical implications

I Helal, GM Fick-Brosnahan, B Reed-Gitomer… - Nature Reviews …, 2012 - nature.com
Glomerular hyperfiltration is a phenomenon that can occur in various clinical conditions
including kidney disease. No single definition of glomerular hyperfiltration has been agreed …

Mechanisms of hypoxia responses in renal tissue

VH Haase - Journal of the american society of nephrology, 2013 - journals.lww.com
Abstract pO 2 in the kidney is maintained at relatively stable levels by a unique and complex
functional interplay between renal blood flow, GFR, O 2 consumption, and arteriovenous O 2 …

Prevalence and risk factors associated with hypertension and prehypertension in a working population at high altitude in China: a cross-sectional study

Y Shen, C Chang, J Zhang, Y Jiang, B Ni… - Environmental health and …, 2017 - Springer
Background Little information is available on the epidemiology of hypertension and
prehypertension at high altitude in China, the aim of this study was to determine the …

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

M Prunotto, A Farina, L Lane, A Pernin, J Schifferli… - Journal of …, 2013 - Elsevier
Urine results from a coordinated activity of glomerular and tubular compartments of the
kidney. As a footprint of these cellular functional processes, urinary exosomes, and 40 …

Untargeted metabolomics analysis on kidney tissues from mice reveals potential hypoxia biomarkers

MI Sajid, FJ Nunez, F Amirrad, MR Roosan, T Vojtko… - Scientific Reports, 2023 - nature.com
Chronic hypoxia may have a huge impact on the cardiovascular and renal systems.
Advancements in microscopy, metabolomics, and bioinformatics provide opportunities to …

[HTML][HTML] Antibiotic intervention exacerbated oxidative stress and inflammatory responses in SD rats under hypobaric hypoxia exposure

Y Liao, Z Chen, Y Yang, D Shen, S Chai, Y Ma… - Free Radical Biology …, 2023 - Elsevier
The gut microbiota plays a crucial role in maintaining host nutrition, metabolism, and
immune homeostasis, particularly in extreme environmental conditions. However, the …

Systemic hypertension at high altitude

O Narvaez-Guerra, K Herrera-Enriquez… - …, 2018 - Am Heart Assoc
568 Hypertension September 2018 prevalence of hypertension with a 2% increase for
every≈ 100 m (≈ 330 ft)-increase in altitude above 3000 mASL (≈ 9800 ft). 16 …

Effects of high altitude on renal physiology and kidney diseases

SY Wang, J Gao, JH Zhao - Frontiers in physiology, 2022 - frontiersin.org
The hypobaric and hypoxic conditions of high-altitude areas exert adverse effects on the
respiratory, circulatory and nervous systems. The kidneys have an abundant blood supply …

Incidence and risk factors of hyperuricemia among 2.5 million Chinese adults during the years 2017–2018

R Shan, Y Ning, Y Ma, X Gao, Z Zhou, C Jin… - International journal of …, 2021 - mdpi.com
Objective: To assess the incidence and risk factors of hyperuricemia among Chinese adults
in 2017–2018. Methods: A total of 2,015,847 adults (mean age 41.2±12.7, 53.1% men) with …

Short-term responses of the kidney to high altitude in mountain climbers

AS Goldfarb-Rumyantzev… - Nephrology Dialysis …, 2014 - academic.oup.com
In high-altitude climbers, the kidneys play a crucial role in acclimatization and in mountain
sickness syndromes [acute mountain sickness (AMS), high-altitude cerebral edema, high …