Neurobiological effects of gallic acid: Current perspectives

MS Bhuia, MM Rahaman, T Islam, MH Bappi… - Chinese Medicine, 2023 - Springer
Gallic acid (GA) is a phenolic molecule found naturally in a wide range of fruits as well as in
medicinal plants. It has many health benefits due to its antioxidant properties. This study …

Molecular, neurochemical, and behavioral hallmarks of reserpine as a model for Parkinson's disease: new perspectives to a long‐standing model

AHFF Leão, AJ Sarmento‐Silva, JR Santos… - Brain …, 2015 - Wiley Online Library
The administration of reserpine to rodents was one of the first models used to investigate the
pathophysiology and screening for potential treatments of P arkinson's disease (PD). The …

Synergistic effect of carnosine on browning of adipose tissue in exercised obese rats; a focus on circulating irisin levels

MF Schaalan, BK Ramadan… - Journal of cellular …, 2018 - Wiley Online Library
The recent appreciation of the energy burning capacity of brown adipose tissue turns it to an
attractive target for anti‐obesity therapy. We sought to evaluate the effect of L‐carnosine on …

Circulating irisin concentrations in rat models of thyroid dysfunction—effect of exercise

DM Samy, CA Ismail, RA Nassra - Metabolism, 2015 - Elsevier
Objectives The speculation that the myokine irisin could regulate whole body energy
expenditure led to the anticipation that irisin may have therapeutic potential in metabolic …

Cognitive, motor and tyrosine hydroxylase temporal impairment in a model of parkinsonism induced by reserpine

JR Santos, JAS Cunha, AL Dierschnabel… - Behavioural brain …, 2013 - Elsevier
Studies have suggested that cognitive deficits can precede motor alterations in Parkinson's
disease (PD). However, in general, classic animal models are based on severe motor …

Effects of exercise training on depression and anxiety with changing neurotransmitters in methamphetamine long term abusers: A narrative review

H Arazi, SS Dadvand, K Suzuki - Biomedical Human Kinetics, 2022 - sciendo.com
Study aim: It is generally accepted that methamphetamine (MA) is a highly addictive
psychostimulant which copies functions of certain neurotransmitters in the brain, and emits …

Running wheel exercise ameliorates methamphetamine‐induced damage to dopamine and serotonin terminals

SJ O'dell, BA Galvez, AJ Ball, JF Marshall - Synapse, 2012 - Wiley Online Library
Repeated administration of methamphetamine (mAMPH) to rodents in a single‐day “binge”
produces long‐lasting damage to dopaminergic and serotonergic terminals. Because …

[HTML][HTML] Effects of oleic acid and/or exercise on diet-induced thermogenesis and obesity in rats: involvement of beige adipocyte differentiation and macrophage M1 …

A Salama, MM Amin, A Hassan - Research in Pharmaceutical …, 2023 - journals.lww.com
Background and purpose: Obesity is a public health problem and the existence of beige
adipocytes has got interested as a potential therapeutic involvement for obesity and obesity …

Physical exercise improves motor and short-term social memory deficits in reserpinized rats

AS Aguiar Jr, AL Araújo, TR da-Cunha, AE Speck… - Brain research …, 2009 - Elsevier
Previous studies have shown that cognitive deficits precede the classical motor symptoms
seen in Parkinson's disease (PD) and that physical exercise may exert beneficial effects on …

Epalrestat improves motor symptoms by reducing oxidative stress and inflammation in the reserpine induced mouse model of Parkinson's disease

MM Rahman, RR Chakraborti, MA Potol… - Animal Models and …, 2020 - Wiley Online Library
Background Parkinson's disease (PD) is a progressive neurodegenerative disorder affecting
a large number of elderly people worldwide. The current therapies for PD are symptom …