Oral squamous cell carcinoma (SCC) is a prevalent malignant disease worldwide,
especially so in Taiwan. Early-or even preclinical-stage detection is critical for reducing …

Oral submucous fibrosis is a potentially malignant disorder of the oral cavity, with a high rate
of malignant transformation. It is very common among habitual areca nut chewers. The …

Background Oral squamous cell carcinoma (OSCC) is the sixth most common cancer
globally. Tobacco consumption and HPV infection, both are the major risk factor for the …

Many oral mucosal lesions are due to substance abuse, such as tobacco and areca nut,
amongst others. There is considerable evidence that oral lesions/disorders such as some …

The overexpression of histone deacetylases (HDACs) has been observed in many cancers
and inhibition of specific HDAC has emerged as a new target for cancer therapy. The …

Oral submucous fibrosis is considered to be a potentially malignant disease caused
primarily due to areca nut chewing. Various theories have been put forth since many …

Background Oral cancers are preceded by oral potentially malignant disorders (OPMD).
Understanding genetic susceptibility for OPMD risk could provide an opportunity for risk …

Purpose Glutathione S-transferases (GSTT1 and GSTM1) are instrumental in detoxification
process of activated carcinogens. Nucleotide excision repair is carried out by DNA helicase …

Oral submucous fibrosis (OSMF) is a chronic, potentially malignant condition of the oral
mucosa and the habitual chewing of areca nut is believed to be the most potent etiological …

Abstract Background In South and Southeast Asian, the majority of buccal squamous cell
carcinoma (BSCC) can arise from oral submucous fibrosis (OSF). BSCCs develop in OSF …