Vimentin expression contributes to cellular mechanoprotection and is a widely recognized
marker of fibroblasts and of epithelial-mesenchymal transition. But it is not understood how …

Intermediate filaments are critical for cell and tissue homeostasis and for stress responses.
Cytoplasmic intermediate filaments form versatile and dynamic assemblies that interconnect …

The endoplasmic reticulum (ER) forms a dynamic network that contacts other cellular
membranes to regulate stress responses, calcium signalling and lipid transfer. Here, using …

Intermediate filaments (IFs) are involved in key cellular functions including polarization,
migration, and protection against large deformations. These functions are related to their …

Cell migration is a vital and dynamic process required for the development of multicellular
organisms and for immune system responses, tissue renewal and wound healing in adults. It …

Retinal scarring with vision loss continues to be an enigma in individuals with advanced age‐
related macular degeneration (AMD). Müller glial cells are believed to initiate and …

Mechanical forces may be generated within a cell due to tissue stiffness, cytoskeletal
reorganization, and the changes (even subtle) in the cell's physical surroundings. These …

The large arrays of cell types in a multicellular organism are defined by their stereotypic size
and/or morphology, and, for cells in vivo, by their anatomic positions. Historically, this identity …

Bacterial infection is a major threat to human health, with infections resulting in considerable
mortality, urging the need for a more profound understanding of bacteria–host interactions …

The role of mechanical signals in the proper functioning of organisms is increasingly
recognised, and every cell senses physical forces and responds to them. These forces are …