Thrombospondins are evolutionarily conserved, calcium-binding glycoproteins that undergo
transient or longer-term interactions with other extracellular matrix components. They share …

Cartilage oligomeric matrix protein (COMP) is a large pentameric glycoprotein that interacts
with multiple extracellular matrix proteins in cartilage and other tissues. While, COMP is …

The growth factor progranulin (PGRN) has been implicated in embryonic development,
tissue repair, tumorigenesis, and inflammation, but its receptors remain unidentified. We …

The genetic basis of most traits is highly polygenic and dominated by non-coding alleles. It is
widely assumed that such alleles exert small regulatory effects on the expression of cis …

Growth retardation resulting in short stature is a major concern for parents and due to its
great variety of causes, a complex diagnostic challenge for clinicians. A major locus involved …

Hypermobility of Joints 4th Edition follows the same format as its successful predecessors.
The aim of which was to provide an overview of hyperlaxity of joints and this edition follows …

▪ Abstract Thrombospondins are secreted, multidomain macromolecules that act as
regulators of cell interactions in vertebrates. Gene knockout mice constructed for two …

Vascular remodeling is the adaptive response to various physiological and
pathophysiological alterations that are closely related to aging and vascular diseases …

The superficial digital flexor tendon (SDFT) is an elastic structure that during maximal
exercise appears to operate close to its functional limits. The biomechanical and …

Cartilage and tendon extracellular matrices are composed of collagens, proteoglycans, and
a number of noncollagenous proteins. Cartilage oligomeric matrix protein (COMP) is a …