Flexible behaviors over long timescales are thought to engage recurrent neural networks in
deep brain regions, which are experimentally challenging to study. In insects, recurrent …

Alcohol is a widely used and abused substance with numerous negative consequences for
human health and safety. Historically, alcohol's widespread, non-specific neurobiological …

A powerful feature of adaptive memory is its inherent flexibility. Alcohol and other addictive
substances can remold neural circuits important for memory to reduce this flexibility …

Alcohol Use Disorder (AUD) is a debilitating disorder that manifests as problematic patterns
of alcohol use. At the core of AUD's behavioral manifestations are the profound structural …

Across the animal kingdom, dopamine plays a crucial role in conferring reinforcement
signals that teach animals about the causal structure of the world. In the fruit fly Drosophila …

Ethanol at low doses induces a locomotor stimulant response across a range of
phylogenetically diverse species. In rodents, this response is commonly used as an index of …

Background Proper regulation of feeding is important for an organism's well-being and
survival and involves a motivational component directing the search for food. Dissecting the …

For all animal species, it is essential to process reward and punishment adaptively in order
to adapt their behaviour to given circumstances. If this processing is disturbed mental …