Vascular stiffness in aging and disease
SF Vatner, J Zhang, C Vyzas, K Mishra… - Frontiers in …, 2021 - frontiersin.org
The goal of this review is to provide further understanding of increased vascular stiffness
with aging, and how it contributes to the adverse effects of major human diseases …
with aging, and how it contributes to the adverse effects of major human diseases …
How does hemodynamics affect rupture tissue mechanics in abdominal aortic aneurysm: Focus on wall shear stress derived parameters, time-averaged wall shear …
An abdominal aortic aneurysm (AAA) is a critical health condition with a risk of rupture,
where the diameter of the aorta enlarges more than 50% of its normal diameter. The …
where the diameter of the aorta enlarges more than 50% of its normal diameter. The …
In vivo cyclic induction of the FOXM1 transcription factor delays natural and progeroid aging phenotypes and extends healthspan
The FOXM1 transcription factor exhibits pleiotropic C-terminal transcriptional and N-terminal
non-transcriptional functions in various biological processes critical for cellular homeostasis …
non-transcriptional functions in various biological processes critical for cellular homeostasis …
Skeleton-secreted PDGF-BB mediates arterial stiffening
Evidence links osteoporosis and cardiovascular disease but the cellular and molecular
mechanisms are unclear. Here we identify skeleton-secreted platelet-derived growth factor …
mechanisms are unclear. Here we identify skeleton-secreted platelet-derived growth factor …
Structural design and mechanical performance of composite vascular grafts
AW Zia, R Liu, X Wu - Bio-Design and Manufacturing, 2022 - Springer
This study reviews the state of the art in structural design and the corresponding mechanical
behaviours of composite vascular grafts. We critically analyse surface and matrix designs …
behaviours of composite vascular grafts. We critically analyse surface and matrix designs …
Biomarkers of aging
Aging Biomarker Consortium, H Bao, J Cao… - Science China Life …, 2023 - Springer
Aging biomarkers are a combination of biological parameters to (i) assess age-related
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …
Cellular, Molecular and Clinical Aspects of Aortic Aneurysm—Vascular Physiology and Pathophysiology
D Domagała, K Data, H Szyller, M Farzaneh… - Cells, 2024 - mdpi.com
A disturbance of the structure of the aortic wall results in the formation of aortic aneurysm,
which is characterized by a significant bulge on the vessel surface that may have …
which is characterized by a significant bulge on the vessel surface that may have …
Cardiac tissue remodeling in healthy aging: the road to pathology
E Tracy, G Rowe, AJ LeBlanc - American Journal of …, 2020 - journals.physiology.org
This review aims to highlight the normal physiological remodeling that occurs in healthy
aging hearts, including changes that occur in contractility, conduction, valve function, large …
aging hearts, including changes that occur in contractility, conduction, valve function, large …
Cardiac aging synthesis from cross-sectional data with conditional generative adversarial networks
Age has important implications for health, and understanding how age manifests in the
human body is the first step for a potential intervention. This becomes especially important …
human body is the first step for a potential intervention. This becomes especially important …
Ex vivo biaxial load testing analysis of aortic biomechanics demonstrates variation in elastic energy distribution across the aortic zone zero
Objectives We hypothesized that tissue characteristics vary significantly along zone zero,
which may be reflected by regional differences in stored elastic energy. Our objectives were …
which may be reflected by regional differences in stored elastic energy. Our objectives were …