Human glioblastoma is the most aggressive type of primary malignant brain tumors.
Standard treatment includes surgical resection followed by radiation and chemotherapy but …

Glioblastoma (GBM), is the most malignant form of gliomas and the most common and lethal
primary brain tumor in adults. Conventional cancer treatments have limited to no efficacy on …

Neural stem cells (NSCs) have garnered significant scientific and commercial interest in the
last 15 years. Given their plasticity, defined as the ability to develop into different phenotypes …

Microglia are the immune cells of the brain, involved in synapse formation, circuit sculpting,
myelination, plasticity, and cognition. Being active players during early development as well …

Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …

Microglial activation is considered as the critical pathogenic event in diverse central nervous
system disorders including cerebral ischemia. Proinflammatory responses of activated …

Adult neurogenesis is a process that generates new and functional neurons from neural
stem cells (NSCs) in a specialized neurogenic niche throughout life. Misregulated …

Background Neonatal stroke is a devastating insult that can lead to life-long impairments. In
response to hypoxic–ischaemic injury, there is loss of neurons and glia as well as a …

The functionality of the central nervous system (CNS) relies on the connection, integration,
and the exchange of information among neural cells. The crosstalk among glial cells and …

Hypoxic‐ischemic encephalopathy (HIE) mainly affects preterm and term newborns, leading
to a high risk of brain damage. Coexisting infection/inflammation and birth asphyxia are key …