The renin-angiotensin system (RAS) is a key player in the control of the cardiovascular
system and hydroelectrolyte balance, with an influence on organs and functions throughout …

Heart failure (HF) remains the most common cause of death and disability, and a major
economic burden, in industrialized nations. Physiological, pharmacological, and clinical …

Thirty years ago, a novel axis of the renin-angiotensin system (RAS) was unveiled by the
discovery of angiotensin-(1− 7)[ANG-(1− 7)] generation in vivo. Later, angiotensin …

The renin‐angiotensin system (RAS) is a critical regulator of hypertension, primarily through
the actions of the vasoactive peptide Ang II, which is generated by the action of angiotensin …

The Mas-related G protein–coupled receptors (Mrgprs or Mas-related genes) comprise a
subfamily of receptors named after the first discovered member, Mas. For most Mrgprs …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the cause of COVID-19, is
reported to increase the rate of mortality worldwide. COVID-19 is associated with acute …

The RAS (renin–angiotensin system) is integral to cardiovascular physiology; however,
dysregulation of this system largely contributes to the pathophysiology of CVD …

The health of the cardiovascular and pulmonary systems is inextricably linked to the renin–
angiotensin system (RAS). Physiologically speaking, a balance between the …

The renin-angiotensin systems (RASs) regulate blood pressure, kidney function, and salt
and water homeostasis. Modulation of RAS is central in the intensive care unit spectrum of …

Our current recognition of the renin-angiotensin system is more convoluted than originally
thought due to the discovery of multiple novel enzymes, peptides, and receptors inherent in …