Recent advances and new strategies in Leishmaniasis diagnosis
RCF De Brito, RDO Aguiar-Soares… - Applied Microbiology …, 2020 - Springer
Leishmaniasis is a set of complex and multifaceted syndromes, with different clinical
manifestations, caused by different species of the genus Leishmania spp. that can be …
manifestations, caused by different species of the genus Leishmania spp. that can be …
Towards a detailed atlas of protein–protein interactions
Highlights•We review current resources that organize experimental knowledge of the
interaction space.•We present the latest efforts in the prediction of interactions and the …
interaction space.•We present the latest efforts in the prediction of interactions and the …
Exosome secretion by the parasitic protozoan Leishmania within the sand fly midgut
VD Atayde, H Aslan, S Townsend, K Hassani… - Cell reports, 2015 - cell.com
Despite several studies describing the secretion of exosomes by Leishmania in vitro,
observation of their formation and release in vivo has remained a major challenge. Herein …
observation of their formation and release in vivo has remained a major challenge. Herein …
Chlamydia trachomatis core genome data mining for promising novel drug targets and chimeric vaccine candidates identification
Chlamydia trachomatis is involved in most sexually transmitted diseases. The species has
emerged as a major public health threat due to its multidrug-resistant capabilities, and new …
emerged as a major public health threat due to its multidrug-resistant capabilities, and new …
Helminth secretomes reflect different lifestyles and parasitized hosts
Helminths cause a number of medical and agricultural problems and are a major cause of
parasitic infections in humans, animals and plants. Comparative analysis of helminth genes …
parasitic infections in humans, animals and plants. Comparative analysis of helminth genes …
Molecular tools-advances, opportunities and prospects for the control of parasites of veterinary importance
The recent advancement in genome sequencing facilities, proteomics, transcriptomics, and
metabolomics of eukaryotes have opened door for employment of molecular diagnostic …
metabolomics of eukaryotes have opened door for employment of molecular diagnostic …
Immunoinformatics Features Linked to Leishmania Vaccine Development: Data Integration of Experimental and In Silico Studies
RCF Brito, FG Guimarães, JPL Velloso… - International journal of …, 2017 - mdpi.com
Leishmaniasis is a wide-spectrum disease caused by parasites from Leishmania genus.
There is no human vaccine available and it is considered by many studies as apotential …
There is no human vaccine available and it is considered by many studies as apotential …
In silico Metabolic Pathway Analysis Identifying Target Against Leishmaniasis – A Kinetic Modeling Approach
The protozoan Leishmania donovani, from trypanosomatids family is a deadly human
pathogen responsible for causing Visceral Leishmaniasis. Unavailability of proper treatment …
pathogen responsible for causing Visceral Leishmaniasis. Unavailability of proper treatment …
An improved interolog mapping-based computational prediction of protein–protein interactions with increased network coverage
Automated and efficient methods that map ortholog interactions from several organisms and
public databases (pDB) are needed to identify new interactions in an organism of interest …
public databases (pDB) are needed to identify new interactions in an organism of interest …
In silico analysis of Leishmania proteomes and protein-protein interaction network: Prioritizing therapeutic targets and drugs for repurposing to treat leishmaniasis
Leishmaniasis is a serious world health problem and its current therapies have several
limitations demanding to develop novel therapeutics for this disease. The present study aims …
limitations demanding to develop novel therapeutics for this disease. The present study aims …