[HTML][HTML] Biomaterials for Testicular Bioengineering: How far have we come and where do we have to go?

BO Horvath-Pereira, GHDR Almeida… - Frontiers in …, 2023 - frontiersin.org
Traditional therapeutic interventions aim to restore male fertile potential or preserve sperm
viability in severe cases, such as semen cryopreservation, testicular tissue, germ cell …

Blood-testis barrier: a review on regulators in maintaining cell junction integrity between Sertoli cells

UR Wanjari, AV Gopalakrishnan - Cell and Tissue Research, 2024 - Springer
The blood-testis barrier (BTB) is formed adjacent to the seminiferous basement membrane. It
is a distinct ultrastructure, partitioning testicular seminiferous epithelium into apical …

Differentiation of human spermatogonial stem cells using a human decellularized testicular scaffold supplemented by platelet‐rich plasma

M Salem, N Feizollahi, A Jabari… - Artificial …, 2023 - Wiley Online Library
Background Effective culture systems for attachment, migration, proliferation, and
differentiation of spermatogonial stem cells (SSCs) can be a promising therapeutic modality …

Motor proteins and spermatogenesis

S Wu, H Li, L Wang, N Mak, X Wu, R Ge, F Sun… - Molecular Mechanisms …, 2021 - Springer
Unlike the intermediate filament-and septin-based cytoskeletons which are apolar
structures, the microtubule (MT) and actin cytoskeletons are polarized structures in …

The non-hormonal male contraceptive adjudin exerts its effects via MAPs and signaling proteins mTORC1/rpS6 and FAK-Y407

L Wang, M Yan, H Li, S Wu, R Ge, CKC Wong… - …, 2021 - academic.oup.com
Abstract Adjudin, 1-(2, 4-dichlorobenzyl)-1H-indazole-3-carbohydrazide (formerly called AF-
2364), is a nonhormonal male contraceptive, since it effectively induces reversible male …

Differentiation and proliferation of spermatogonial stem cells using a three-dimensional decellularized testicular scaffold: a new method to study the testicular …

S Naeemi, A Eidi, R Khanbabaee… - … urology and nephrology, 2021 - Springer
Purpose Successful in vitro transplantation of spermatogonial stem cells (SSCs) demands
effective culture systems for SSCs proliferation and differentiation. Natural extracellular …

Using carbohydrate‐based polymers to facilitate testicular regeneration

A Majeed, H Afzal, K Maqsood, A Noureen… - Biology of the …, 2024 - Wiley Online Library
Male infertility is a significant global issue affecting 60–80 million people, with 40%–50% of
cases linked to male issues. Exposure to radiation, drugs, sickness, the environment, and …

[HTML][HTML] Биологическая активность лекарственного препарата из полипептидов семенников в модели окислительного стресса in vitro

ЮА Хоченкова, ЮС Мачкова… - Экспериментальная …, 2022 - cyberleninka.ru
Введение. Мужское бесплодие является одной из основных причин вынужденной
бездетности пар во всем мире. В настоящий момент на рынке представлено …

Protective Effects of Curcumin, Coumarin and Honey against Diclofenac Sodium-induced Testicular Dysfunction in Adult Mice

IMH El Mileegy, NS Abou Khalil… - Journal of Advanced …, 2023 - advetresearch.com
Although diclofenac (DS) is used in treating a wide variety of painful and inflammatory
situations in humans and animals, its chronic administration is accompanied by side effects …

Laminins and matrix metalloproteinases connection: a subtle relationship that can go wrong in a tumor context, particularly if CD44 gets involved

P Rousselle, K Beck - The Extracellular Matrix and the Tumor …, 2022 - Springer
Laminins (LM) are large extracellular glycoproteins involved in several biological processes,
including cellular interactions, self-polymerization, and binding with other extracellular …