Chronic obstructive pulmonary disease exacerbation fundamentals: Diagnosis, treatment, prevention and disease impact

M MacLeod, A Papi, M Contoli, B Beghé, BR Celli… - …, 2021 - Wiley Online Library
In chronic obstructive pulmonary disease (COPD), exacerbations (ECOPD), characterized
by an acute deterioration in respiratory symptoms, are fundamental events impacting …

Pediatric bronchiectasis: no longer an orphan disease

V Goyal, K Grimwood, J Marchant… - Pediatric …, 2016 - Wiley Online Library
Bronchiectasis is described classically as a chronic pulmonary disorder characterized by a
persistent productive cough and irreversible dilatation of one or more bronchi. However, in …

An updated definition and severity classification of chronic obstructive pulmonary disease exacerbations: the Rome proposal

BR Celli, LM Fabbri, SD Aaron, A Agusti… - American journal of …, 2021 - atsjournals.org
Over 200 years ago, René Laennec published the first description of emphysema, an
important pathobiological element of what is today known as chronic obstructive pulmonary …

Management of COPD exacerbations: a European respiratory society/American thoracic society guideline

JA Wedzicha, M Miravitlles, JR Hurst… - European …, 2017 - Eur Respiratory Soc
This document provides clinical recommendations for treatment of chronic obstructive
pulmonary disease (COPD) exacerbations. Comprehensive evidence syntheses, including …

[HTML][HTML] C-reactive protein testing to guide antibiotic prescribing for COPD exacerbations

CC Butler, D Gillespie, P White, J Bates… - … England Journal of …, 2019 - Mass Medical Soc
Background Point-of-care testing of C-reactive protein (CRP) may be a way to reduce
unnecessary use of antibiotics without harming patients who have acute exacerbations of …

Spanish guideline for COPD (gesEPOC). Update 2014

M Miravitlles, JJ Soler-Cataluña, M Calle… - Archivos de …, 2014 - Elsevier
The publication of the Spanish guideline for chronic obstructive pulmonary disease–COPD–
(GesEPOC) has brought about a change in the approach to the treatment of this disease …

Leitlinie zur Diagnostik und Therapie von Patienten mit chronisch obstruktiver Bronchitis und Lungenemphysem (COPD)

C Vogelmeier, R Buhl, O Burghuber, CP Criée… - …, 2018 - thieme-connect.com
Das vorliegende Dokument ist eine Neufassung und Aktualisierung der Leitlinie zur
Diagnostik und Therapie von Patienten mit COPD, die die bisherige Version aus dem Jahr …

Guía española de la EPOC (GesEPOC). Actualización 2014

M Miravitlles, JJ Soler-Cataluña, M Calle… - Archivos de …, 2014 - Elsevier
The main cause of this disease is considered to be smoking or exposure to other gases and
harmful particles that cause an inflammatory reaction in the airways and lung parenchyma …

Chronic respiratory infection in patients with chronic obstructive pulmonary disease: what is the role of antibiotics?

M Miravitlles, A Anzueto - International journal of molecular sciences, 2017 - mdpi.com
Chronic infections are associated with exacerbation in patients with chronic obstructive
pulmonary disease (COPD). The major objective of the management of these patients is the …

A systematic review and meta-analysis of sputum purulence to predict bacterial infection in COPD exacerbations

K Chen, KA Pleasants, RA Pleasants… - COPD: Journal of …, 2020 - Taylor & Francis
Abstract The 2020 Global Initiative for Obstructive Lung Disease (GOLD) Report highlights
the importance of sputum purulence in the decision to prescribe antibiotics for acute …