Nanoparticle design strategies for enhanced anticancer therapy by exploiting the tumour microenvironment

Y Dai, C Xu, X Sun, X Chen - Chemical Society Reviews, 2017 - pubs.rsc.org
Nanovehicles can efficiently carry and deliver anticancer agents to tumour sites. Compared
with normal tissue, the tumour microenvironment has some unique properties, such as …

[HTML][HTML] A review on anti-cancer effect of green tea catechins

Z Cheng, Z Zhang, Y Han, J Wang, Y Wang… - Journal of functional …, 2020 - Elsevier
This article reviewed inhibitory activities of green tea catechins (GTCs) against various
tumorigenesis and their suppressive effects on cancer cell progression, metastasis, and …

Liposome-based drug co-delivery systems in cancer cells

SZ Vahed, R Salehi, S Davaran, S Sharifi - Materials Science and …, 2017 - Elsevier
Combination therapy and nanotechnology offer a promising therapeutic method in cancer
treatment. By improving drug's pharmacokinetics, nanoparticulate systems increase the …

The use of human umbilical vein endothelial cells (HUVECs) as an in vitro model to assess the toxicity of nanoparticles to endothelium: a review

Y Cao, Y Gong, L Liu, Y Zhou, X Fang… - Journal of Applied …, 2017 - Wiley Online Library
With the rapid development of nanotechnologies, nanoparticles (NPs) are increasingly
produced and used in many commercial products, which could lead to the contact of human …

Techniques for accurate sizing of gold nanoparticles using dynamic light scattering with particular application to chemical and biological sensing based on aggregate …

T Zheng, S Bott, Q Huo - ACS applied materials & interfaces, 2016 - ACS Publications
Gold nanoparticles (AuNPs) have found broad applications in chemical and biological
sensing, catalysis, biomolecular imaging, in vitro diagnostics, cancer therapy, and many …

Nanobody-based delivery systems for diagnosis and targeted tumor therapy

Y Hu, C Liu, S Muyldermans - Frontiers in immunology, 2017 - frontiersin.org
The development of innovative targeted therapeutic approaches are expected to surpass the
efficacy of current forms of treatments and cause less damage to healthy cells surrounding …

Tumour microenvironment responsive nanoconstructs for cancer theranostic

A Gulzar, J Xu, C Wang, F He, D Yang, S Gai, P Yang… - Nano today, 2019 - Elsevier
The tumour mass is made up of not only of a heterogeneous population of cancer cells
nonetheless also a mixture of resident as well as the infiltrating host cells, secreted factors …

[HTML][HTML] Not only P-glycoprotein: Amplification of the ABCB1-containing chromosome region 7q21 confers multidrug resistance upon cancer cells by coordinated …

I Genovese, A Ilari, YG Assaraf, F Fazi… - Drug Resistance Updates, 2017 - Elsevier
The development of drug resistance continues to be a dominant hindrance toward curative
cancer treatment. Overexpression of a wide-spectrum of ATP-dependent efflux pumps, and …

Personalized nanomedicine: a revolution at the nanoscale

C Fornaguera, MJ García-Celma - Journal of personalized medicine, 2017 - mdpi.com
Nanomedicine is an interdisciplinary research field that results from the application of
nanotechnology to medicine and has the potential to significantly improve some current …

Nanoparticle delivery of anticancer drugs overcomes multidrug resistance in breast cancer

Y Yuan, T Cai, X Xia, R Zhang, P Chiba, Y Cai - Drug delivery, 2016 - Taylor & Francis
Breast cancer is a serious threat to women's health, because multidrug resistance (MDR)
has hampered treatment and prognosis. Nanodelivery of anticancer agents is a new …