Modeling developmental brain diseases using human pluripotent stem cells-derived brain organoids–progress and perspective
Developmental brain diseases encompass a group of conditions resulting from genetic or
environmental perturbations during early development. Despite the increased research …
environmental perturbations during early development. Despite the increased research …
Involvement of vascular endothelial growth factor in schizophrenia
A Rampino, T Annese, S Torretta, R Tamma… - Neuroscience …, 2021 - Elsevier
Vascular endothelial growth factor (VEGF), which acts as an angiogenic and neurotrophic
factor, is involved the regulation of cerebral blood volume and flow in Schizophrenia (SCZ) …
factor, is involved the regulation of cerebral blood volume and flow in Schizophrenia (SCZ) …
Honokiol improves depression-like behaviors in rats by HIF-1α-VEGF signaling pathway activation
XX Fan, WY Sun, Y Li, Q Tang, LN Li, X Yu… - Frontiers in …, 2022 - frontiersin.org
Increasing evidence indicates that the pathogenesis of depression is closely linked to
impairments in neuronal synaptic plasticity. Honokiol, a biologically active substance …
impairments in neuronal synaptic plasticity. Honokiol, a biologically active substance …
Correlation of BDNF, VEGF, TNF‐α, and S100B with cognitive impairments in chronic, medicated schizophrenia patients
P Chukaew, N Bunmak, N Auampradit… - …, 2022 - Wiley Online Library
Cognitive impairment is a prominent cause of disability in schizophrenia. Although
antipsychotic drugs can rescue the psychotic symptoms, the cognitive impairments persist …
antipsychotic drugs can rescue the psychotic symptoms, the cognitive impairments persist …
Overdispersed gene expression in schizophrenia
Schizophrenia (SCZ) is a severe, highly heterogeneous psychiatric disorder with varied
clinical presentations. The polygenic genetic architecture of SCZ makes identification of …
clinical presentations. The polygenic genetic architecture of SCZ makes identification of …
Preventive and therapeutic effects of environmental enrichment in Wistar rats submitted to neonatal hypoxia-ischemia
LE Durán-Carabali, DM Arcego, EF Sanches… - Behavioural brain …, 2019 - Elsevier
Environmental enrichment (EE) at early stages of neurodevelopment attenuates HI-induced
behavioral, histological and cellular damage. However, the effects of EE exposure during …
behavioral, histological and cellular damage. However, the effects of EE exposure during …
Neurodevelopmental concepts of schizophrenia in the genome-wide association era: AKT/mTOR signaling as a pathological mediator of genetic and environmental …
Normative brain development is contingent on the complex interplay between genes and
environment. Schizophrenia (SCZ) is considered a highly polygenic, neurodevelopmental …
environment. Schizophrenia (SCZ) is considered a highly polygenic, neurodevelopmental …
It takes two to tango: Widening our understanding of the onset of schizophrenia from a neuro-angiogenic perspective
BS Casas, D Arancibia-Altamirano… - Frontiers in Cell and …, 2022 - frontiersin.org
Schizophrenia is a chronic debilitating mental disorder characterized by perturbations in
thinking, perception, and behavior, along with brain connectivity deficiencies …
thinking, perception, and behavior, along with brain connectivity deficiencies …
Translational control in neurovascular brain development
K Chalkiadaki, E Statoulla… - Royal Society …, 2021 - royalsocietypublishing.org
The human brain carries out complex tasks and higher functions and is crucial for
organismal survival, as it senses both intrinsic and extrinsic environments. Proper brain …
organismal survival, as it senses both intrinsic and extrinsic environments. Proper brain …
Blood biomarkers for neonatal hypoxic–ischemic encephalopathy in the presence and absence of sentinel events
Objective To determine if neonatal serum biomarkers representing different pathways of
injury differ for cases of HIE of unknown cause to gain insight into timing and mechanism of …
injury differ for cases of HIE of unknown cause to gain insight into timing and mechanism of …