Introduction The translational gap from the discovery of evidence-based solutions to their
implementation in healthcare delivery organizations derives from an incorrect assumption …

Sickle cell disease (SCD) is a medical condition in which chronic pain is common and
negatively impacts psychosocial function and quality of life. Although the brain mechanisms …

Background While there is a known association between low vitamin D levels and increased
chronic pain in patients with Sickle Cell Disease (SCD), there are no reported studies …

Background SCD poses a significant healthcare burden. Understanding the factors
contributing to high healthcare utilization and readmissions is crucial for improving the …

Introduction. Sickle cell disease (SCD) is a chronic disease characterized by debilitating
bone pains which commonly necessitate the use of analgesic drugs including opioids and …

Introduction: opioids are a mainstay in sickle cell disease (SCD) pain care. Opioids are
known to cause physical and/or psychological dependence. Increasingly, a significant …

Background Opioid use disorder (OUD) among adolescents with sickle cell disease (SCD)
patients increases their risk of complications from sickle cell disease, such as infections …

BACKGROUND: Prolonged use of pentazocine in sickle cell disease (SCD) because of
chronic pain may result in mental dependence (addiction) and/or physical dependence …

Sickle cell disease, one of the world's most common genetic disorders is prevalent in sub-
Saharan Africa. The trans-Atlantic slave trade accounted for the gene movement from Africa …

Introduction: Sickle cell disease (SCD) is a genetic disorder that is widely observed on a
global scale and known for its substantial negative impact on health and mortality. The …