[HTML][HTML] Focus: Organelles: Lipid droplets and the management of cellular stress

E Jarc, T Petan - The Yale journal of biology and medicine, 2019 - ncbi.nlm.nih.gov
Lipid droplets are cytosolic fat storage organelles present in most eukaryotic cells. Long
regarded merely as inert fat reservoirs, they are now emerging as major regulators of …

Lipid droplet functions beyond energy storage

MA Welte, AP Gould - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2017 - Elsevier
Lipid droplets are cytoplasmic organelles that store neutral lipids and are critically important
for energy metabolism. Their function in energy storage is firmly established and …

Lipid droplets in the nervous system

I Ralhan, CL Chang, J Lippincott-Schwartz… - Journal of Cell …, 2021 - rupress.org
Lipid droplets are dynamic intracellular lipid storage organelles that respond to the
physiological state of cells. In addition to controlling cell metabolism, they play a protective …

Lipid droplet biogenesis

TC Walther, J Chung… - Annual review of cell and …, 2017 - annualreviews.org
Lipid droplets (LDs) are ubiquitous organelles that store neutral lipids for energy or
membrane synthesis and act as hubs for metabolic processes. Cells generate LDs de novo …

Lipid droplet availability affects neural stem/progenitor cell metabolism and proliferation

M Ramosaj, S Madsen, V Maillard, V Scandella… - Nature …, 2021 - nature.com
Neural stem/progenitor cells (NSPCs) generate new neurons throughout adulthood.
However, the underlying regulatory processes are still not fully understood. Lipid …

Expanding roles for lipid droplets

MA Welte - Current biology, 2015 - cell.com
Lipid droplets are the intracellular sites for neutral lipid storage. They are critical for lipid
metabolism and energy homeostasis, and their dysfunction has been linked to many …

The biophysics and cell biology of lipid droplets

AR Thiam, RV Farese Jr, TC Walther - Nature reviews Molecular cell …, 2013 - nature.com
Lipid droplets are intracellular organelles that are found in most cells, where they have
fundamental roles in metabolism. They function prominently in storing oil-based reserves of …

Regulation of glucose and lipid metabolism in health and disease

L Chen, XW Chen, X Huang, BL Song, Y Wang… - Science China life …, 2019 - Springer
Glucose and fatty acids are the major sources of energy for human body. Cholesterol, the
most abundant sterol in mammals, is a key component of cell membranes although it does …

Lipid droplet contact sites in health and disease

E Herker, G Vieyres, M Beller, N Krahmer… - Trends in Cell Biology, 2021 - cell.com
After having been disregarded for a long time as inert fat drops, lipid droplets (LDs) are now
recognized as ubiquitous cellular organelles with key functions in lipid biology and beyond …

The assembly of lipid droplets and their roles in challenged cells

WM Henne, ML Reese, JM Goodman - The EMBO journal, 2018 - embopress.org
Cytoplasmic lipid droplets are important organelles in nearly every eukaryotic and some
prokaryotic cells. Storing and providing energy is their main function, but they do not work in …