[HTML][HTML] Measurements methods for the development of MicroRNA-based tests for cancer diagnosis

F Precazzini, S Detassis, AS Imperatori… - International journal of …, 2021 - mdpi.com
Studies investigating microRNAs as potential biomarkers for cancer, immune-related
diseases, or cardiac pathogenic diseases, among others, have exponentially increased in …

[HTML][HTML] PNA-based microRNA detection methodologies

E Cadoni, A Manicardi, A Madder - Molecules, 2020 - mdpi.com
MicroRNAs (miRNAs or miRs) are small noncoding RNAs involved in the fine regulation of
post-transcriptional processes in the cell. The physiological levels of these short (20–22 …

Direct detection of alpha satellite DNA with single-base resolution by using abasic Peptide Nucleic Acids and Fluorescent in situ Hybridization

A Robles-Remacho, MA Luque-Gonzalez… - Biosensors and …, 2023 - Elsevier
The detection of repetitive sequences with single-base resolution is becoming increasingly
important aiming to understand the biological implications of genomic variation in these …

Quantum dot nanoconjugates for immuno-detection of circulating cell-free miRNAs

R Shandilya, AM Sobolev, N Bunkar, A Bhargava… - Talanta, 2020 - Elsevier
Argonaute protein (AGO2) bound circulating cell-free miRNAs (ccf-miRs), in the recent
years, has attracted great attention due to their differential abundance in biological fluids. In …

[HTML][HTML] Open a new window in the world of circulating microRNAs by merging ChemiRNA Tech with a Luminex platform

A Marín-Romero, M Tabraue-Chávez, JW Dear… - Sensors & …, 2022 - pubs.rsc.org
microRNAs are small noncoding RNA molecules showing huge promise as biomarkers and
diagnostic tools for illnesses, as significant changes in their expression occur in response to …

A label-free activatable biosensor for in situ detection of exosomal microRNAs based on DNA-AgNCs and hairpin type nucleic acid probes

D Li, QW Li, H Xiang, SS Yuan, XP Yang - Analytical Methods, 2024 - pubs.rsc.org
Exosomal microRNA (miRNA) is a potential biomarker for cancer diagnosis, metastasis, and
treatment. In situ detection of exosomal miRNA is an attractive option due to its simplicity and …

[HTML][HTML] SARS-CoV-2 viral RNA detection using the novel CoVradar device associated with the CoVreader smartphone app

C Martín-Sierra, MT Chavez, P Escobedo… - Biosensors and …, 2023 - Elsevier
The COVID-19 pandemic has highlighted the need for innovative approaches to its
diagnosis. Here we present CoVradar, a novel and simple colorimetric method that …

[HTML][HTML] Simultaneous detection of drug-induced liver injury protein and microRNA biomarkers using dynamic chemical labelling on a luminex MAGPIX system

A Marín-Romero, M Tabraue-Chávez… - Analytica, 2021 - mdpi.com
Drug-induced liver injury (DILI) is a potentially fatal adverse event and a leading cause for
pre-and post-marketing drug withdrawal. Several multinational DILI initiatives have now …

[HTML][HTML] Multiplexed MicroRNA Biomarker Detection by Bridging Lifetime Filtering Imaging and Dynamic Chemistry Labeling

M Padial-Jaudenes, M Tabraue-Chávez… - Sensors and Actuators B …, 2024 - Elsevier
MicroRNAs (miRs) have emerged as promising biomarkers for early disease diagnosis and
personalized treatment monitoring. However, their clinical utility has been hampered by …

[HTML][HTML] SA-ODG platform: a semi-automated and PCR-free method to analyse microRNAs in solid tissues

S Detassis, F Precazzini, I Brentari, R Ruffilli, C Ress… - Analyst, 2024 - pubs.rsc.org
Over the past two decades, numerous techniques have been developed for analysing
microRNAs in body fluids and tissues. However, these techniques still face technical …