Key determinants of success in fecal microbiota transplantation: From microbiome to clinic

S Porcari, N Benech, M Valles-Colomer, N Segata… - Cell host & …, 2023 - cell.com
Fecal microbiota transplantation (FMT) has achieved satisfactory results in preventing the
recurrence of Clostridioides difficile infection, but these positive outcomes have only been …

Gut microbiome, metabolome, host immunity associated with inflammatory bowel disease and intervention of fecal microbiota transplantation

R Wu, R Xiong, Y Li, J Chen, R Yan - Journal of Autoimmunity, 2023 - Elsevier
Gut dysbiosis has been associated with inflammatory bowel disease (IBD), one of the most
common gastrointestinal diseases. The microbial communities play essential roles in host …

Recipient-independent, high-accuracy FMT-response prediction and optimization in mice and humans

O Shtossel, S Turjeman, A Riumin, MR Goldberg… - Microbiome, 2023 - Springer
Background Some microbiota compositions are associated with negative outcomes,
including among others, obesity, allergies, and the failure to respond to treatment …

Long-term environmental levels of microcystin-LR exposure induces colorectal chronic inflammation, fibrosis and barrier disruption via CSF1R/Rap1b signaling …

Y Yang, H Wang, X Wang, L Chen, W Liu, D Cai… - Journal of Hazardous …, 2022 - Elsevier
Abstract Microcystin-LR (MC-LR) is a very common toxic cyanotoxins threating ecosystems
and the public health. This study aims to explore the long-term effects and potential toxicity …

[HTML][HTML] Composition of intestinal flora affects the risk relationship between Alzheimer's disease/Parkinson's disease and cancer

Z Hang, T Lei, Z Zeng, S Cai, W Bi, H Du - Biomedicine & Pharmacotherapy, 2022 - Elsevier
An increasing number of epidemiological studies have shown that there is a significant
inverse relationship between the onset of Alzheimer's disease/Parkinson's disease (AD/PD) …

The role of fecal microbiota transplantation in the treatment of inflammatory bowel disease

M Stojek, A Jabłońska, K Adrych - Journal of Clinical Medicine, 2021 - mdpi.com
The exact pathogenesis of inflammatory bowel disease (IBD) is still not completely
understood. It is hypothesized that a genetic predisposition leads to an exaggerated immune …

[HTML][HTML] Gut microbial metabolome in inflammatory bowel disease: From association to therapeutic perspectives

M Li, L Yang, C Mu, Y Sun, Y Gu, D Chen, T Liu… - Computational and …, 2022 - Elsevier
Inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis
(UC), is a set of clinically chronic, relapsing gastrointestinal inflammatory disease and lacks …

Alteration of gut microbiota relates to metabolic disorders in primary aldosteronism patients

Y Liu, Q Jiang, Z Liu, S Shen, J Ai, Y Zhu… - Frontiers in …, 2021 - frontiersin.org
Purpose This study aimed to determine the relationships among gut microbiota, primary
aldosteronism (PA), and related metabolic disorders. Methods The study enrolled 13 PA …

Strain-resolved analysis in a randomized trial of antibiotic pretreatment and maintenance dose delivery mode with fecal microbiota transplant for ulcerative colitis

BJ Smith, Y Piceno, M Zydek, B Zhang, LA Syriani… - Scientific reports, 2022 - nature.com
Fecal microbiota transplant is a promising therapy for ulcerative colitis. Parameters
maximizing effectiveness and tolerability are not yet clear, and it is not known how import the …

Oral konjac glucomannan for prevention of ionizing radiation-induced injury by regulating gut microbiota and increasing short chain fatty acids

D Liu, B Zhuang, M Wei, T Yuan, J Li, P Deng… - International Journal of …, 2023 - Elsevier
Ionizing radiation-induced injury commonly happens in radiotherapy, leading to damages of
the hematopoietic and gastrointestinal systems. Radioprotective medications are mainly …