[HTML][HTML] Regulation of the hypothalamic-pituitary-adrenocortical stress response

JP Herman, JM McKlveen, S Ghosal… - Comprehensive …, 2016 - ncbi.nlm.nih.gov
The hypothalamo-pituitary-adrenocortical (HPA axis) is required for stress adaptation.
Activation of the HPA axis causes secretion of glucocorticoids, which act on multiple organ …

Sex differences in the hypothalamic–pituitary–adrenal axis' response to stress: an important role for gonadal hormones

AL Heck, RJ Handa - Neuropsychopharmacology, 2019 - nature.com
The hypothalamic–pituitary–adrenal (HPA) axis, a neuroendocrine network that controls
hormonal responses to internal and external challenges in an organism's environment …

The cortisol switch between vulnerability and resilience

ER de Kloet, M Joëls - Molecular Psychiatry, 2024 - nature.com
In concert with neuropeptides and transmitters, the end products of the hypothalamus-
pituitary-adrenal (HPA) axis, the glucocorticoid hormones cortisol and corticosterone …

A users guide to HPA axis research

RL Spencer, T Deak - Physiology & behavior, 2017 - Elsevier
Glucocorticoid hormones (cortisol and corticosterone-CORT) are the effector hormones of
the hypothalamic-pituitary-adrenal (HPA) axis neuroendocrine system. CORT is a systemic …

Assessment of spatial learning and memory in the Barnes maze task in rodents—methodological consideration

K Gawel, E Gibula, M Marszalek-Grabska… - Naunyn-Schmiedeberg's …, 2019 - Springer
Among the methods valuable for assessing spatial learning and memory impairments in
rodents, the Barnes maze (BM) task deserves special attention. It is based on the …

Sex differences in stress-related psychiatric disorders: neurobiological perspectives

DA Bangasser, RJ Valentino - Frontiers in neuroendocrinology, 2014 - Elsevier
Stress is associated with the onset and severity of several psychiatric disorders that occur
more frequently in women than men, including posttraumatic stress disorder (PTSD) and …

Dynamics and correlation of serum cortisol and corticosterone under different physiological or stressful conditions in mice

S Gong, YL Miao, GZ Jiao, MJ Sun, H Li, J Lin, MJ Luo… - PloS one, 2015 - journals.plos.org
Although plasma corticosterone is considered the main glucocorticoid involved in regulation
of stress responses in rodents, the presence of plasma cortisol and whether its level can be …

Coping with the forced swim stressor: towards understanding an adaptive mechanism

ER De Kloet, ML Molendijk - Neural plasticity, 2016 - Wiley Online Library
In the forced swim test (FST) rodents progressively show increased episodes of immobility if
immersed in a beaker with water from where escape is not possible. In this test, a compound …

[PDF][PDF] Sex differences in the HPA axis

N Goel, JL Workman, TT Lee, L Innala, V Viau - Compr Physiol, 2014 - academia.edu
The hypothalamic-pituitary-adrenal (HPA) axis is a major component of the systems that
respond to stress, by coordinating the neuroendocrine and autonomic responses. Tightly …

Salivary cortisol as a biomarker in stress research

DH Hellhammer, S Wüst, BM Kudielka - Psychoneuroendocrinology, 2009 - Elsevier
Salivary cortisol is frequently used as a biomarker of psychological stress. However,
psychobiological mechanisms, which trigger the hypothalamus–pituitary–adrenal axis …