The causal relationship between endothelin-1 and hypertension: focusing on endothelial dysfunction, arterial stiffness, vascular remodeling, and blood pressure …

K Kostov - Life, 2021 - mdpi.com
Hypertension (HTN) is one of the most prevalent diseases worldwide and is among the most
important risk factors for cardiovascular and cerebrovascular complications. It is currently …

Serum concentrations of endothelin-1 and matrix metalloproteinases-2,-9 in pre-hypertensive and hypertensive patients with type 2 diabetes

K Kostov, A Blazhev, M Atanasova… - International journal of …, 2016 - mdpi.com
Endothelin-1 (ET-1) is one of the most potent vasoconstrictors known to date. While its
plasma or serum concentrations are elevated in some forms of experimental and human …

Circulating levels of endothelin-1 and big endothelin-1 in patients with essential hypertension

K Kostov, A Blazhev - Pathophysiology, 2021 - mdpi.com
The role of endothelin-1 (ET-1) in the pathogenesis of hypertension (HTN) is not clearly
established. There is evidence that its circulating levels are elevated in some forms of …