Autophagy and exosomes; inter-connected maestros in Alzheimer's disease

HB Atya, NM Sharaf, RM Abdelghany… - …, 2024 - Springer
Autophagy is a crucial process involved in the degradation and recycling of cytoplasmic
components which are transported to the lysosomal compartment by autophagosomes …

Neurotoxic effects of chloroquine and its main transformation product formed after chlorination

S Hu, J Zhao, S Fang, K Guo, W Qi, H Liu - Science of The Total …, 2024 - Elsevier
Pharmaceutical transformation products (TPs) generated during wastewater treatment have
become an environmental concern. However, there is limited understanding regarding the …

Hippocampal Proteomic Analysis in Male Mice Following Aggressive Behavior Induced by Long-Term Administration of Perampanel

W Yang, L Ma, DM Hai, N Liu, JM Yang, XB Lan… - ACS …, 2022 - ACS Publications
Antiepileptic drugs have been shown to be associated with inducing or exacerbating
adverse psychotropic reaction, including aggressive behavior. Perampanel, the first …

Autonomic behavioral impairment induced by simazine exposure during early life of male mouse is mediated by Lmx1a/Wnt1 pathway

X Li, X Hu, Y Jiang, D Wang, T Wang… - Environmental …, 2022 - Wiley Online Library
Simazine is a widely used herbicide and known as an environmental estrogen. Multiple
studies have proved simazine can induced the degeneration of dopaminergic neuron …

Combined Acetaminophen and L-carnosine Treatment Prevented Anxiety-like Behaviour in Chronic Constriction Injury-induced Peripheral Neuropathy

VB Owoyele, AO Bakare, F Olaseinde, MJ Ochu… - 2023 - researchsquare.com
Background Emotional derangement contributes to the worsening quality of life in a patient
suffering from neuropathic pain (NP). Here, we report the therapeutic beneficial effects of …