Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?

SE Engelen, AJB Robinson, YX Zurke… - Nature Reviews …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall, characterized by the
formation of plaques containing lipid, connective tissue and immune cells in the intima of …

Combating physical inactivity during the COVID-19 pandemic

AJ Pinto, DW Dunstan, N Owen, E Bonfá… - Nature Reviews …, 2020 - nature.com
Physical inactivity is common during periods of self-isolation, but for patients with rheumatic
diseases, there are crucial benefits to be gained from maintaining an active lifestyle …

The effects of tumour necrosis factor inhibitors, methotrexate, non-steroidal anti-inflammatory drugs and corticosteroids on cardiovascular events in rheumatoid arthritis …

C Roubille, V Richer, T Starnino, C McCourt… - Annals of the …, 2015 - ard.bmj.com
The objective of this systematic literature review was to determine the association between
cardiovascular events (CVEs) and antirheumatic drugs in rheumatoid arthritis (RA) and …

Atherosclerotic cardiovascular disease prevention in rheumatoid arthritis

AG Semb, E Ikdahl, G Wibetoe, C Crowson… - Nature Reviews …, 2020 - nature.com
Patients with rheumatoid arthritis (RA) are at high risk of developing cardiovascular disease
(CVD). Inflammation has a pivotal role in the pathogenesis of CVD. RA is an inflammatory …

Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force

JS Smolen, FC Breedveld, GR Burmester… - Annals of the …, 2016 - ard.bmj.com
Background Reaching the therapeutic target of remission or low-disease activity has
improved outcomes in patients with rheumatoid arthritis (RA) significantly. The treat-to-target …

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update

JS Smolen, R Landewé, FC Breedveld… - Annals of the …, 2014 - ard.bmj.com
In this article, the 2010 European League against Rheumatism (EULAR) recommendations
for the management of rheumatoid arthritis (RA) with synthetic and biological disease …

Atherosclerosis in rheumatoid arthritis: is it all about inflammation?

S Skeoch, IN Bruce - Nature Reviews Rheumatology, 2015 - nature.com
Rheumatoid arthritis (RA) has long been associated with increased cardiovascular risk, but
despite substantial improvements in disease management, mortality remains high …

The epidemiology of established rheumatoid arthritis

T Otón, L Carmona - Best Practice & Research Clinical Rheumatology, 2019 - Elsevier
No published epidemiological study has specifically focused on the prevalence of
established rheumatoid arthritis (RA), as epidemiologists do not study established RA …

Mortality in patients with rheumatoid arthritis: a 15-year prospective cohort study

J Van den Hoek, HC Boshuizen, LD Roorda… - Rheumatology …, 2017 - Springer
The aim of this study was to investigate (a) the mortality in a clinical cohort of patients with
established rheumatoid arthritis in comparison with the general Dutch population over 15 …

Impact of Janus kinase inhibitors on risk of cardiovascular events in patients with rheumatoid arthritis: systematic review and meta-analysis of randomised controlled …

W Xie, Y Huang, S Xiao, X Sun, Y Fan… - Annals of the rheumatic …, 2019 - ard.bmj.com
Objectives To investigate the effect of Janus kinase inhibitors (Jakinibs) on cardiovascular
risk in adult patients with rheumatoid arthritis (RA) via a meta-analysis of randomised …