Transdermal microneedle (MN) patches are a promising tool used to transport a wide variety
of active compounds into the skin. To serve as a substitute for common hypodermic needles …

Transdermal drug delivery using microneedles is increasingly gaining interest due to the
issues associated with oral drug delivery routes. Gastrointestinal route exposes the drug to …

Microneedle (MN) patches consisting of miniature needles have emerged as a promising
tool to perforate the stratum corneum and translocate biomolecules into the dermis in a …

Skin infections caused by bacteria, viruses and fungi are difficult to treat by conventional
topical administration because of poor drug penetration across the stratum corneum. This …

Polymeric microparticles (MPs) are recognized as very popular carriers to increase the
bioavailability and bio-distribution of both lipophilic and hydrophilic drugs. Among different …

The minimally-invasive and painless nature of microneedle (MN) application has enabled
the technology to obviate many issues with injectable drug delivery. MNs not only administer …

Nature contains abundant systems that can significantly alter their structures and properties
to adapt to the surrounding environment. Through natural selection and unceasing …

Microneedles (MNs) are microscopic needles that are applied to the skin in a minimally
invasive way to facilitate transdermal drug delivery and/or uptake of interstitial fluid from the …

Methotrexate (MTX), typically used as its sodium salt (MTX Na), is a first-line treatments for
moderate to severe psoriasis, showing good efficacy. However, its systemic administration is …

Introduction During the last decades, the ever-increasing proportion of patients with cancer
has been led to serious concerns worldwide. Therefore, the development and use of novel …