Assembly of the exosporium layer in Clostridioides difficile spores

D Paredes-Sabja, F Cid-Rojas… - Current Opinion in …, 2022 - Elsevier
Clostridioides difficile is a Gram-positive, spore-forming obligate anaerobe and a major
threat to the healthcare system world-wide. Because of its strict anaerobic requirements, the …

Targeting the impossible: a review of new strategies against endospores

A Romero-Rodríguez, B Ruiz-Villafán… - Antibiotics, 2023 - mdpi.com
Endospore-forming bacteria are ubiquitous, and their endospores can be present in food, in
domestic animals, and on contaminated surfaces. Many spore-forming bacteria have been …

SpoVG is an important regulator of sporulation and affects biofilm formation by regulating Spo0A transcription in Bacillus cereus 0–9

Q Huang, Z Zhang, Q Liu, F Liu, Y Liu, J Zhang… - BMC microbiology, 2021 - Springer
Abstract Background Bacillus cereus 0–9, a Gram-positive, endospore-forming bacterium
isolated from healthy wheat roots in our previous research, is considered to be an effective …

Contributions of crust proteins to spore surface properties in Bacillus subtilis

B Shuster, M Khemmani, K Abe, X Huang… - Molecular …, 2019 - Wiley Online Library
Surface properties, such as adhesion and hydrophobicity, constrain dispersal of bacterial
spores in the environment. In Bacillus subtilis, these properties are influenced by the …

Expansion of the spore surface polysaccharide layer in Bacillus subtilis by deletion of genes encoding glycosyltransferases and glucose modification enzymes

B Shuster, M Khemmani, Y Nakaya… - Journal of …, 2019 - Am Soc Microbiol
Polysaccharides (PS) decorate the surface of dormant endospores (spores). In the model
organism for sporulation, Bacillus subtilis, the composition of the spore PS is not known in …

Bacillus anthracis and other Bacillus species

CK Cote, JD Heffron, SO Bailey, SL Welkos… - Molecular medical …, 2024 - Elsevier
The genus Bacillus is a diverse group of spore-forming bacteria. Bacillus species have
implications in both medical and biodefense aspects of microbiology. This chapter attempts …

Role of novel polysaccharide layers in assembly of the exosporium, the outermost protein layer of the Bacillus anthracis spore

D Lehmann, M Sladek, M Khemmani… - Molecular …, 2022 - Wiley Online Library
A fundamental question in cell biology is how cells assemble their outer layers. The bacterial
endospore is a well‐established model for cell layer assembly. However, the assembly of …

ExsY, CotY, and CotE effects on Bacillus anthracis outer spore layer architecture

J Durand-Heredia, HY Hsieh, BM Thompson… - Journal of …, 2022 - Am Soc Microbiol
Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis are the major pathogens of the
spore-forming genus Bacillus and possess an outer spore layer, the exosporium, not found …

[HTML][HTML] Is there a role for Intestinal Sporobiota in the Antimicrobial Resistance Crisis?

A Romero-Rodríguez, B Ruíz-Villafán, S Sánchez… - Microbiological …, 2024 - Elsevier
Antimicrobial resistance (AMR) is a complex issue requiring specific, multi-sectoral
measures to slow its spread. When people are exposed to antimicrobial agents, it can cause …

The morphogenetic protein CotE positions exosporium proteins CotY and ExsY during sporulation of Bacillus cereus

A Lablaine, M Serrano, C Bressuire-Isoard, S Chamot… - MSphere, 2021 - Am Soc Microbiol
The exosporium is the outermost spore layer of some Bacillus and Clostridium species and
related organisms. It mediates the interactions of spores with their environment, modulates …