Primary tumors are responsible for 10% of cancer deaths. In most cases, the main cause of
mortality is the formation of metastases. Accumulating evidence suggests that a …

Cancer is a disease exhibiting uncontrollable cell growth and spreading to other parts of the
organism. It is a heavy, worldwide burden for mankind with high morbidity and mortality …

Cancer cell dormancy is a common feature of human tumors and represents a major clinical
barrier to the long-term efficacy of anticancer therapies. Dormant cancer cells, either in …

ABSTRACT Three‐dimensional (3D) cell culture models are becoming increasingly popular
in contemporary cancer research and drug resistance studies. Recently, scientists have …

There is an urgent need to identify targeting molecules to control invasion and metastasis in
cancer patients. We first isolated cancer stem cells (CSCs) from SKOV3 ovarian cancer cells …

Therapy-resistant cancer stem cells (CSCs) contribute to the poor clinical outcomes of
patients with recurrent glioblastoma (rGBM) who fail standard of care (SOC) therapy …

A spaceflight has enormous influence on the health of space voyagers due to the combined
effects of microgravity and cosmic radiation. Known effects of microgravity (μ g) on cells are …

Emerging evidence implicates cancer stem cells (CSCs) as primary determinants of the
clinical behavior of human cancers, representing an ideal target for next-generation anti …

Background Head and Neck squamous cell carcinoma (HNSCC) is a human lethal cancer
with clinical, pathological, phenotypical and biological heterogeneity. Caner initiating cells …

Cancer stem cells are increasingly becoming a primary target for new cancer treatment
development. The ability to study their transient behavior in vitro will provide the opportunity …