The role of Sphingolipids in myelination and myelin stability and their involvement in childhood and adult demyelinating disorders
P Giussani, A Prinetti, C Tringali - Journal of neurochemistry, 2021 - Wiley Online Library
Multiple sclerosis (MS) represents the most common demyelinating disease affecting the
central nervous system (CNS) in adults as well as in children. Furthermore, in children, in …
central nervous system (CNS) in adults as well as in children. Furthermore, in children, in …
[HTML][HTML] Lysosomal ceramide metabolism disorders: implications in Parkinson's disease
S Paciotti, E Albi, L Parnetti, T Beccari - Journal of clinical medicine, 2020 - mdpi.com
Ceramides are a family of bioactive lipids belonging to the class of sphingolipids.
Sphingolipidoses are a group of inherited genetic diseases characterized by the …
Sphingolipidoses are a group of inherited genetic diseases characterized by the …
[HTML][HTML] Treatment with CD52 antibody protects neurons in experimental autoimmune encephalomyelitis mice during the recovering phase
W Hao, Q Luo, MD Menger, K Fassbender… - Frontiers in …, 2021 - frontiersin.org
Multiple sclerosis (MS) is a chronic autoimmune disease driven by T and B lymphocytes.
The remyelination failure and neurodegeneration results in permanent clinical disability in …
The remyelination failure and neurodegeneration results in permanent clinical disability in …
[HTML][HTML] Sphingolipids in thyroid eye disease
A Gulbins, GE Görtz, E Gulbins… - Frontiers in Endocrinology, 2023 - frontiersin.org
Graves' disease (GD) is caused by an autoimmune formation of autoantibodies and
autoreactive T-cells against the thyroid stimulating hormone receptor (TSHR). The …
autoreactive T-cells against the thyroid stimulating hormone receptor (TSHR). The …
[HTML][HTML] Sapropterin (BH4) aggravates autoimmune encephalomyelitis in mice
K Schmitz, S Trautmann, L Hahnefeld, C Fischer… - …, 2021 - Elsevier
Depletion of the enzyme cofactor, tetrahydrobiopterin (BH4), in T-cells was shown to prevent
their proliferation upon receptor stimulation in models of allergic inflammation in mice …
their proliferation upon receptor stimulation in models of allergic inflammation in mice …
[图书][B] The Beneficial Impact of Exercise on Mechanisms of Neurodegeneration: Potential Therapeutic Approach for Multiple Sclerosis
A Weaver - 2021 - search.proquest.com
Recent evidence suggests that exercise can improve outcomes in multiple
neurodegenerative disorders through stimulation of neurotrophic factors, anti-inflammatory …
neurodegenerative disorders through stimulation of neurotrophic factors, anti-inflammatory …