Red blood cell transfusions have reduced morbidity and mortality for patients with sickle cell
disease. Transfusions can lead to erythrocyte alloimmunization, however, with serious …

Transfusions can be a life-saving treatment of patients with sickle-cell disease (SCD).
However, availability of matched units can be limiting because of distinctive blood group …

Sickle cell disease (SCD) patients are at increased risk of red blood cell (RBC)
alloimmunization. Recipient inflammatory state at time of transfusion has been shown to …

Red blood cell (RBC) transfusions can be life‐sustaining in chronic inherited anaemias,
such as thalassaemia, and the indications for blood transfusions in patients with sickle cell …

Background Transfusions are the primary therapy for thalassemia but have significant
cumulative risks. In 2004, the C enters for D isease C ontrol and P revention (CDC) …

BACKGROUND Although red blood cell (RBC) transfusion represents an integral
component of sickle cell disease (SCD) care, transfusion support for some patients can …

Red blood cell (RBC) transfusions are a milestone in the treatment for sickle cell anaemia
(SSA) and for thalassaemia. RBC alloimmunization remains a major challenge of chronic …

Alloimmunization against red blood cell (RBC) antigens is a cause of morbidity and mortality
in transfused patients with sickle cell disease (SCD). To investigate distinguishing …

Red blood cell (RBC) alloimmunization may occur following transfusion or
pregnancy/delivery. Although observational human studies have described the …

BACKGROUND The reason for the difference in susceptibility to red blood cell (RBC)
alloimmunization among patients with sickle cell disease (SCD) is not clearly understood …