Immune modulation in sepsis, ARDS, and Covid-19—the road traveled and the road ahead
A Leligdowicz, MO Harhay, CS Calfee - NEJM evidence, 2022 - evidence.nejm.org
Immune Modulation in Sepsis, ARDS, and Covid-19 — The Road Traveled and the Road Ahead
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Ex vivo and in vitro monocyte responses do not reflect in vivo immune responses and tolerance
A Jansen, N Bruse, N Waalders, J Gerretsen… - Journal of Innate …, 2023 - karger.com
Cytokine production by ex vivo (EV)-stimulated leukocytes is commonly used to gauge
immune function and frequently proposed to guide immunomodulatory therapy. However …
immune function and frequently proposed to guide immunomodulatory therapy. However …
Plasma protein biomarkers reflective of the host response in patients developing Intensive Care Unit-acquired pneumonia
TSR van Engelen, TDY Reijnders, FP Paling… - Critical care, 2023 - Springer
Background Immune suppression has been implicated in the occurrence of pneumonia in
critically ill patients. We tested the hypothesis that Intensive Care Unit (ICU)-acquired …
critically ill patients. We tested the hypothesis that Intensive Care Unit (ICU)-acquired …
BACTERIAL PATHOGEN–ASSOCIATED MOLECULAR PATTERNS UPREGULATE HUMAN GLUCOCORTICOID RECEPTOR EXPRESSION IN PERIPHERAL …
DG Greenhalgh, TL Green, D Lim, K Cho - Shock, 2022 - journals.lww.com
It is well known that bacterial components (pathogen-associated molecular patterns
[PAMPs]) induce a proinflammatory response through pattern recognition receptor signaling …
[PAMPs]) induce a proinflammatory response through pattern recognition receptor signaling …
α2-Adrenoreceptor antagonist ameliorates sepsis-associated pulmonary fibrosis by suppressing norepinephrine-mediated fibroblast differentiation via inhibiting PKC …
X Su, F Lu, Y Chen, M Wang, G Tang, W Lin, Y Liu… - Shock, 2023 - journals.lww.com
Pulmonary fibrosis is an important factor affecting the prognosis of severe septic patients
with acute lung injury. The objective of this study was to explore the effect of NE and α 2 …
with acute lung injury. The objective of this study was to explore the effect of NE and α 2 …
MPC1 regulates endotoxin tolerance of macrophages through mitochondrial oxidative stress resistance
Y Liu, F Qi, H Zeng, D Huang, W Zhang, Y Zhang… - 2024 - researchsquare.com
Increasing evidence highlights the crucial role of endotoxin tolerance in the regulation of the
sepsis, yet its underlying mechanisms remain poorly understood. Here, we provide evidence …
sepsis, yet its underlying mechanisms remain poorly understood. Here, we provide evidence …
Role of Circular RNA ASPH in Macrophage Polarization and Response in Sepsis
TZ Wang - 2023 - search.proquest.com
Circular RNAs (circRNAs), a novel non-coding RNA species generated by back-splicing,
have been shown to participate in gene regulation of leukocytes. Our previous RNA …
have been shown to participate in gene regulation of leukocytes. Our previous RNA …
[PDF][PDF] Untersuchungen zur Wirksamkeit antimikrobieller Peptide gegen bovine Mastitispathogene in vitro und zu Komponenten des angeborenen Immunsystems in …
JK Schneider - 2023 - edoc.ub.uni-muenchen.de
PMN Polymorphkernige neutrophile Granulozyten PRR Pathogen-Recognition-Rezeptoren
PVP Polyvinylpyrrolidon R2 Bestimmtheitsmaß RAGE Receptor for advanced glycation …
PVP Polyvinylpyrrolidon R2 Bestimmtheitsmaß RAGE Receptor for advanced glycation …