Chemistries for DNA nanotechnology
M Madsen, KV Gothelf - Chemical reviews, 2019 - ACS Publications
The predictable nature of DNA interactions enables the programmable assembly of highly
advanced 2D and 3D DNA structures of nanoscale dimensions. The access to ever larger …
advanced 2D and 3D DNA structures of nanoscale dimensions. The access to ever larger …
Cancer biomarker detection: recent achievements and challenges
L Wu, X Qu - Chemical Society Reviews, 2015 - pubs.rsc.org
The early detection of cancer can significantly reduce cancer mortality and saves lives. Thus,
a great deal of effort has been devoted to the exploration of new technologies to detect early …
a great deal of effort has been devoted to the exploration of new technologies to detect early …
Multiplexed 3D cellular super-resolution imaging with DNA-PAINT and Exchange-PAINT
Super-resolution fluorescence microscopy is a powerful tool for biological research, but
obtaining multiplexed images for a large number of distinct target species remains …
obtaining multiplexed images for a large number of distinct target species remains …
Playing with the molecules of life
DD Young, PG Schultz - ACS chemical biology, 2018 - ACS Publications
Our understanding of the complex molecular processes of living organisms at the molecular
level is growing exponentially. This knowledge, together with a powerful arsenal of tools for …
level is growing exponentially. This knowledge, together with a powerful arsenal of tools for …
Targeting the N terminus for site-selective protein modification
CB Rosen, MB Francis - Nature chemical biology, 2017 - nature.com
The formation of well-defined protein bioconjugates is critical for many studies and
technologies in chemical biology. Tried-and-true methods for accomplishing this typically …
technologies in chemical biology. Tried-and-true methods for accomplishing this typically …
Scaling by shrinking: empowering single-cell'omics' with microfluidic devices
Recent advances in cellular profiling have demonstrated substantial heterogeneity in the
behaviour of cells once deemed'identical', challenging fundamental notions of …
behaviour of cells once deemed'identical', challenging fundamental notions of …
Beyond traditional biosensors: recent advances in gold nanoparticles modified electrodes for biosensing applications
Gold nanoparticles (AuNPs) have emerged as powerful tools in the construction of highly
sensitive electrochemical biosensors. Their unique properties, such as the ability to serve as …
sensitive electrochemical biosensors. Their unique properties, such as the ability to serve as …
Synthesis of site-specific antibody-drug conjugates using unnatural amino acids
JY Axup, KM Bajjuri, M Ritland… - Proceedings of the …, 2012 - National Acad Sciences
Antibody-drug conjugates (ADCs) allow selective targeting of cytotoxic drugs to cancer cells
presenting tumor-associated surface markers, thereby minimizing systemic toxicity …
presenting tumor-associated surface markers, thereby minimizing systemic toxicity …
Applying CRISPR-Cas12a as a signal amplifier to construct biosensors for non-DNA targets in ultralow concentrations
J Li, S Yang, C Zuo, L Dai, Y Guo, G Xie - Acs Sensors, 2020 - ACS Publications
Efficient signal amplification is essential to construct ultrasensitive biosensors for biologically
relevant species with abundant concomitant interferences. Here, we apply LbaCas12a as a …
relevant species with abundant concomitant interferences. Here, we apply LbaCas12a as a …
Oriented immobilization of proteins on solid supports for use in biosensors and biochips: a review
Y Liu, J Yu - Microchimica Acta, 2016 - Springer
Immobilization of proteins on a solid support is critical with respect to the fabrication and
performance of biosensors and biochips. Protein attachment with a preferable orientation …
performance of biosensors and biochips. Protein attachment with a preferable orientation …