Glucocorticoids regulate fundamental processes of the human body and control cellular
functions such as cell metabolism, growth, differentiation, and apoptosis. Moreover …

Approximately 5–10% of asthmatic patients worldwide suffer from severe asthma.
Experimental and clinical studies have demonstrated that IL-13 is an important cytokine in …

Asthma | From Bronchoconstriction to Airways Inflammation and Remodeling | American
Journal of Respiratory and Critical Care Medicine ATS Journals Logo Official Publications …

The pathogenesis of asthma reflects, in part, the activity of T cell cytokines. Murine models
support participation of interleukin-4 (IL-4) and the IL-4 receptor in asthma. Selective …

Allergic inflammation is due to a complex interplay between several inflammatory cells,
including mast cells, basophils, lymphocytes, dendritic cells, eosinophils, and sometimes …

Evidence accumulated over the last 5‐10 years indicates that glucocorticoids (GCs) inhibit
the production of interleukin (IL)‐12, interferon (IFN)‐γ, IFN‐α, and tumor necrosis factor …

▪ Abstract Interleukin-12 (IL-12) is a heterodimeric cytokine that plays a central role in
promoting type 1 T helper cell (Th1) responses and, hence, cell-mediated immunity. Its …

▪ Abstract The incidence, morbidity, and mortality of asthma has increased worldwide over
the last two decades. Asthma is a complex inflammatory disease of the lung characterized …

Bronchial asthma is a complex disorder that is thought to arise as a result of aberrant T‐
lymphocyte responses to noninfectious environmental antigens. In particular, the symptoms …

Continuing Medical Education examination CONTINUING MEDICAL EDUCATION
ARTICLECredit can now be obtained, free for a limited time, by reading the following review …