Background Critically ill people may lose fluid because of serious conditions, infections (eg
sepsis), trauma, or burns, and need additional fluids urgently to prevent dehydration or …

While complex physiological mechanisms exist to regulate and optimize tissue oxygenation
under various conditions, clinical and experimental evidence indicates that anaemia …

A doença cardíaca isquêmica, principal determinante da PCR, continua liderando as
causas de morte no mundo, e no Brasil não é diferente. 1, 2 Em 2013, nos Estados Unidos …

Background Each year, worldwide, about 3 million people die as a result of trauma, many
after reaching hospital. Among trauma patients who do survive to reach hospital, bleeding is …

Background The current common and dogmatic opinion is that whole-body computed
tomography (WBCT) should not be performed in major trauma patients in shock. We aimed …

BACKGROUND Aggressive fluid resuscitation in trauma promotes deleterious effects such
as clot disruption, dilutional coagulopathy and hypothermia. Animal studies suggest that …

Efforts to create platelet-like structures for the augmentation of haemostasis have focused
solely on recapitulating aspects of platelet adhesion; more complex platelet behaviours such …

Objectives Sustained changes in resuscitation and transfusion management have been
observed since the turn of the millennium, along with an ongoing discussion of surgical …

Hemorrhagic shock (HS) management is based on a timely, rapid, definitive source control
of bleeding/s and on blood loss replacement. Stopping the hemorrhage from progressing …

Death due to trauma is the leading cause of lost life years worldwide, with haemorrhage
being responsible for 30-40% of trauma mortality and accounting for almost 50% of the …