Impedance Spectroscopy for Bacterial Cell Monitoring, Analysis, and Antibiotic Susceptibility Testing

P Swami, S Anand, A Holani, S Gupta - Langmuir, 2024 - ACS Publications
Conventional approaches for bacterial cell analysis are hindered by lengthy processing
times and tedious protocols that rely on gene amplification and cell culture. Impedance …

On the compatibility of single-cell microcarriers (nanovials) with microfluidic impedance cytometry

C Brandi, A De Ninno, F Ruggiero, E Limiti… - Lab on a Chip, 2024 - pubs.rsc.org
We investigate for the first time the compatibility of nanovials with microfluidic impedance
cytometry (MIC). Nanovials are suspendable crescent-shaped single-cell microcarriers that …

CRISPR/Cas9-Mediated Genome Editing of T4 Bacteriophage for High-Throughput Antimicrobial Susceptibility Testing

Y He, J Chen - Analytical Chemistry, 2024 - ACS Publications
The accurate and effective determination of antimicrobial resistance is essential to limiting
the spread of infectious diseases and ensuring human health. Herein, a simple, accurate …

Phosphorylation-amplified synchronized droplet microfluidics sensitizes bacterial growth kinetic real-time monitoring

J Zhong, Y Chang, M Liang, Y Zhou, Y Ai - Biosensors and Bioelectronics, 2024 - Elsevier
The necessity for rapid and accurate bacterial growth monitoring is imperative across
various domains, including healthcare and environmental safety. We introduce the self …

Comprehensive evaluation of clinical antimicrobial resistance using impedance-accelerated single-bacterium multiplex screening strategy

Y Chang, J Zhong, AKB Kassim, SH Koo, TY Tan… - Sensors and Actuators B …, 2025 - Elsevier
Rapid detection of bacterial antibiotic resistance is paramount in clinical settings to enable
timely and effective therapeutic interventions. Traditional approaches such as disc diffusion …

Navigating regulatory and analytical challenges in live biotherapeutic product development and manufacturing

Microbiome Therapeutics Innovation Group… - Frontiers in …, 2024 - frontiersin.org
The recent FDA approvals of Rebyota™ and Vowst™ represent landmark milestones within
the burgeoning field of live microbiota-based products. Future microbiota-based treatment …