[HTML][HTML] Microfluidic Technologies for High Throughput Screening Through Sorting and On-Chip Culture of C. elegans
D Midkiff, A San-Miguel - Molecules, 2019 - mdpi.com
The nematode Caenorhabditis elegans is a powerful model organism that has been widely
used to study molecular biology, cell development, neurobiology, and aging. Despite their …
used to study molecular biology, cell development, neurobiology, and aging. Despite their …
[HTML][HTML] Geroscience approaches to increase healthspan and slow aging
S Melov - F1000Research, 2016 - ncbi.nlm.nih.gov
For decades, researchers in the biology of aging have focused on defining mechanisms that
modulate aging by primarily studying a single metric, sometimes described as the “gold …
modulate aging by primarily studying a single metric, sometimes described as the “gold …
[HTML][HTML] NeuroChip: A Microfluidic Electrophysiological Device for Genetic and Chemical Biology Screening of Caenorhabditis elegans Adult and Larvae
Genetic and chemical biology screens of C. elegans have been of enormous benefit in
providing fundamental insight into neural function and neuroactive drugs. Recently the …
providing fundamental insight into neural function and neuroactive drugs. Recently the …
Microfluidic platform for integrated compartmentalization of single zoospores, germination and measurement of protrusive force generated by germ tubes
This paper describes the design, fabrication and characterisation of a novel monolithic lab-
on-a-chip (LOC) platform combining the trapping and germination of individual zoospores of …
on-a-chip (LOC) platform combining the trapping and germination of individual zoospores of …
[HTML][HTML] Analyzing the locomotory gaitprint of Caenorhabditis elegans on the basis of empirical mode decomposition
LC Lin, HS Chuang - PloS one, 2017 - journals.plos.org
The locomotory gait analysis of the microswimmer, Caenorhabditis elegans, is a commonly
adopted approach for strain recognition and examination of phenotypic defects. Gait is also …
adopted approach for strain recognition and examination of phenotypic defects. Gait is also …
[PDF][PDF] The use of lab-on-a-chip devices to measure the forces exerted by pathogenic oomycete species
H Shearer - 2018 - ir.canterbury.ac.nz
Oomycetes in the genus Phytophthora cause devastating diseases worldwide, resulting in
billions of dollars of economic damage annually. Although the control of these oomycetes is …
billions of dollars of economic damage annually. Although the control of these oomycetes is …
Microfluidic device for studying nematodes
SA Vanapalli, M Rahman - US Patent 10,668,467, 2020 - Google Patents
A microfluidic device includes a substrate, a cover layer and one or more chambers
disposed within the cover layer, the substrate or both. Each chamber has a first end, a …
disposed within the cover layer, the substrate or both. Each chamber has a first end, a …
Biophysical Phenotyping of Caenorhabditis Elegans in a Microfluidic Chip for Quantitative Drug Screening
S Sofela - 2020 - search.proquest.com
Drug discovery requires screening for potential synthetic or natural compounds from a vast
number of libraries and therefore, is a lengthy process. To accurately measure drug efficacy …
number of libraries and therefore, is a lengthy process. To accurately measure drug efficacy …
Microfluidic electrophysiological device for genetic and chemical biology screening of nematodes
C Hu - 2013 - eprints.soton.ac.uk
Genetic and chemical biology screens of C. elegans have been of enormous benefit in
providing fundamental insight into neural function and neuroactive drugs. Recently the …
providing fundamental insight into neural function and neuroactive drugs. Recently the …