The C-type lectins are a superfamily of proteins that recognize a broad repertoire of ligands
and that regulate a diverse range of physiological functions. Most research attention has …

The immune and skeletal systems share a variety of molecules, including cytokines,
chemokines, hormones, receptors, and transcription factors. Bone cells interact with immune …

The bone is an essential organ for locomotion and protection of the body, as well as
hematopoiesis and mineral homeostasis. In order to exert these functions throughout life …

Bone homeostasis is securely controlled by the dynamic well‐balanced actions among
osteoclasts, osteoblasts and osteocytes. Osteoclasts are large multinucleated cells that …

Myeloid cells are key drivers of physiological responses to pathogen invasion or tissue
damage. Members of the C-type lectin receptor (CLR) family stand out among the …

Myeloid-derived suppressor cells (MDSCs) are a heterogenous population of immature
myeloid cells whose numbers dramatically increase in chronic and acute inflammatory …

Several important events occur at the maternal–fetal interface, including generation of
maternal–fetal tolerance, remodeling of the uterine smooth muscle and its spiral arteries and …

Pathophysiology of rheumatoid arthritis : Current Opinion in Rheumatology
Pathophysiology of rheumatoid arthritis : Current Opinion in Rheumatology Log in or …

The innate immune system consists of a variety of elements controlling and participating in
virtually all aspects of inflammation and immunity. It is crucial for host defense, but on the …

Osteoclasts are myeloid lineage-derived bone-resorbing cells of hematopoietic origin. They
differentiate from myeloid precursors through a complex regulation process where the …