[HTML][HTML] Conscious processing and the global neuronal workspace hypothesis

GA Mashour, P Roelfsema, JP Changeux, S Dehaene - Neuron, 2020 - cell.com
We review the central tenets and neuroanatomical basis of the global neuronal workspace
(GNW) hypothesis, which attempts to account for the main scientific observations regarding …

Differential cortical network engagement during states of un/consciousness in humans

R Zelmann, AC Paulk, F Tian, GAB Villegas, JD Peralta… - Neuron, 2023 - cell.com
What happens in the human brain when we are unconscious? Despite substantial work, we
are still unsure which brain regions are involved and how they are impacted when …

The cortical connectome of primate lateral prefrontal cortex

R Xu, NP Bichot, A Takahashi, R Desimone - Neuron, 2022 - cell.com
The lateral prefrontal cortex (LPFC) of primates plays an important role in executive control,
but how it interacts with the rest of the cortex remains unclear. To address this, we densely …

Topological analysis of differential effects of ketamine and propofol anaesthesia on brain dynamics

TF Varley, V Denny, O Sporns… - Royal Society open …, 2021 - royalsocietypublishing.org
Research has found that the vividness of conscious experience is related to brain dynamics.
Despite both being anaesthetics, propofol and ketamine produce different subjective states …

Propofol-induced unresponsiveness is associated with a brain network phase transition

RM Pullon, CE Warnaby, JW Sleigh - Anesthesiology, 2022 - pubs.asahq.org
Background The wakeful brain can easily access and coordinate a large repertoire of
different states—dynamics suggestive of “criticality.” Anesthesia causes loss of criticality at …

Propofol-mediated Unconsciousness Disrupts Progression of Sensory Signals through the Cortical Hierarchy

JM Tauber, SL Brincat, EP Stephen… - Journal of Cognitive …, 2024 - ieeexplore.ieee.org
A critical component of anesthesia is the loss of sensory perception. Propofol is the most
widely used drug for general anesthesia, but the neural mechanisms of how and when it …

Propofol anesthesia decreased the efficiency of long-range cortical interaction in humans

Z Liang, X Jin, Y Ren, T Yu, X Li - IEEE Transactions on …, 2021 - ieeexplore.ieee.org
Objective: Phase-amplitude coupling (PAC) has recently been used to illuminate cross-
frequency coordination in neurophysiological activity of electroencephalogram. However …

Changes in information integration and brain networks during propofol-, dexmedetomidine-, and ketamine-induced unresponsiveness

Z Liang, Y Chang, X Liu, S Cao, Y Chen, T Wang… - British Journal of …, 2024 - Elsevier
Background Information integration and network science are important theories for
quantifying consciousness. However, whether these theories propose drug-or conscious …

Frontal cortical functional connectivity is impacted by anaesthesia in macaques

C Giacometti, A Dureux, D Autran-Clavagnier… - Cerebral …, 2022 - academic.oup.com
A critical aspect of neuroscience is to establish whether and how brain networks evolved
across primates. To date, most comparative studies have used resting-state functional …

Dynamic alpha-gamma phase-amplitude coupling signatures during sevoflurane-induced loss and recovery of consciousness

J Liu, K Dong, SS Low, Q Wei, G Wang, F Huang… - Neuroscience …, 2022 - Elsevier
Phase-amplitude coupling (PAC) plays an important role in anesthetic-induced
unconsciousness. The delta-alpha PAC signature during anesthetic-induced …