Osteosarcoma: current status of immunotherapy and future trends
K Mori, F Rédini, F Gouin, B Cherrier… - Oncology …, 2006 - spandidos-publications.com
Osteosarcoma is the most common primary bone tumor and represents a major therapeutic
challenge in medical oncology. While the use of aggressive chemotherapy has drastically …
challenge in medical oncology. While the use of aggressive chemotherapy has drastically …
Mitochondrial p32 is a critical mediator of ARF-induced apoptosis
K Itahana, Y Zhang - Cancer cell, 2008 - cell.com
The shared exon 2 of the p14ARF-p16INK4a locus is frequently mutated in human cancers.
However, in contrast to the exon 1β-encoded N-terminal half of ARF, the function of the exon …
However, in contrast to the exon 1β-encoded N-terminal half of ARF, the function of the exon …
[HTML][HTML] The use of adenoviral vectors in gene therapy and vaccine approaches
NM Araújo, IGS Rubio, NPA Toneto… - … and Molecular Biology, 2022 - SciELO Brasil
Adenovirus was first identified in the 1950s and since then this pathogenic group of viruses
has been explored and transformed into a genetic transfer vehicle. Modification or deletion …
has been explored and transformed into a genetic transfer vehicle. Modification or deletion …
P53 represses human papillomavirus type 16 DNA replication via the viral E2 protein
Abstract Background Human papillomavirus (HPV) DNA replication can be inhibited by the
cellular tumour suppressor protein p53. However, the mechanism through which p53 inhibits …
cellular tumour suppressor protein p53. However, the mechanism through which p53 inhibits …
Enforced expression of p14ARF induces p53-dependent cell cycle arrest but not apoptosis
Expression of the p14ARF tumour suppressor is induced by hyperproliferative signals
produced by RAS, MYC and other oncogenes. p14ARF quenches inappropriate mitogenic …
produced by RAS, MYC and other oncogenes. p14ARF quenches inappropriate mitogenic …
Молекулярные основы дизрегуляции программированной гибели лимфоцитов при хронической вирусной инфекции
ВВ Новицкий, НВ Рязанцева… - Бюллетень сибирской …, 2006 - cyberleninka.ru
В статье анализируются данные современной литературы и результаты собственных
исследований о роли дисбаланса программированной клеточной гибели в …
исследований о роли дисбаланса программированной клеточной гибели в …
Loss of LZAP inactivates p53 and regulates sensitivity of cells to DNA damage in a p53-dependent manner
JJ Wamsley, C Gary, A Biktasova, M Hajek, G Bellinger… - Oncogenesis, 2017 - nature.com
Chemotherapy and radiation, the two most common cancer therapies, exert their anticancer
effects by causing damage to cellular DNA. However, systemic treatment damages DNA not …
effects by causing damage to cellular DNA. However, systemic treatment damages DNA not …
Апоптоз и вирусная инфекция
ОБ Жукова, НВ Рязанцева, ВВ Новицкий - 2006 - elibrary.ru
В монографии рассматриваются актуальные вопросы современной медико-
биологической науки, касающиеся иммунологический аспектов формирования …
биологической науки, касающиеся иммунологический аспектов формирования …
[PDF][PDF] Expression and clinical significance of tbx2 in pancreatic cancer
S Duo, T Tiao-Dong, Z Lei, W Wei, S Hong-Li… - Asian Pac J Cancer …, 2009 - Citeseer
TBX2 is one of the family of genes encoding developmental transcription factors,
characterized by a 200 amino acid DNA binding domain (T-box), found to be related to …
characterized by a 200 amino acid DNA binding domain (T-box), found to be related to …
Topotecan enhances immune clearance of gliomas
J Wei, G DeAngulo, W Sun, SF Hussain… - Cancer immunology …, 2009 - Springer
Despite aggressive surgery, radiation therapy, and chemotherapy, glioblastoma multiforme
(GBM) is refractory to therapy, recurs quickly, and results in a median survival time of only 14 …
(GBM) is refractory to therapy, recurs quickly, and results in a median survival time of only 14 …